[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …
pathological conditions, four-chamber heart models have only been addressed recently; …
Inverse problems in blood flow modeling: A review
D Nolte, C Bertoglio - International journal for numerical …, 2022 - Wiley Online Library
Mathematical and computational modeling of the cardiovascular system is increasingly
providing non‐invasive alternatives to traditional invasive clinical procedures. Moreover, it …
providing non‐invasive alternatives to traditional invasive clinical procedures. Moreover, it …
A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …
accurately modeling their arrangement is essential for simulating heart electrophysiology …
[HTML][HTML] Electro-mechanical whole-heart digital twins: a fully coupled multi-physics approach
T Gerach, S Schuler, J Fröhlich, L Lindner… - Mathematics, 2021 - mdpi.com
Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …
medicine and support clinical decision making by providing a powerful tool to understand …
Active force generation in cardiac muscle cells: mathematical modeling and numerical simulation of the actin-myosin interaction
Cardiac in silico numerical simulations are based on mathematical models describing the
physical processes involved in the heart function. In this review paper, we critically survey …
physical processes involved in the heart function. In this review paper, we critically survey …
[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …
wherein biophysically detailed core models describe the different physical processes …
[HTML][HTML] A machine learning method for real-time numerical simulations of cardiac electromechanics
We propose a machine learning-based method to build a system of differential equations
that approximates the dynamics of 3D electromechanical models for the human heart …
that approximates the dynamics of 3D electromechanical models for the human heart …
[HTML][HTML] 3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …
[HTML][HTML] Machine learning of multiscale active force generation models for the efficient simulation of cardiac electromechanics
High fidelity (HF) mathematical models describing the generation of active force in the
cardiac muscle tissue typically feature a large number of state variables to capture the …
cardiac muscle tissue typically feature a large number of state variables to capture the …