Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment

Q Yin, SY Song, Y Bian, Y Wang, A Deng, J Lv… - Frontiers in …, 2024 - frontiersin.org
Background The interaction between pyroptosis—a form of programmed cell death—and
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …

[HTML][HTML] Hepatitis C virus and hepatocellular carcinoma: carcinogenesis in the era of direct-acting antivirals

F Fiehn, C Beisel, M Binder - Current Opinion in Virology, 2024 - Elsevier
Chronic hepatitis C virus (HCV) infection is a major cause of hepatic fibrosis and cirrhosis,
with a risk for the development of hepatocellular carcinoma (HCC). Although highly effective …

Premature mortality trends in 183 countries by cancer type, sex, WHO region, and World Bank income level in 2000–19: a retrospective, cross-sectional, population …

SS Murthy, D Trapani, B Cao, F Bray, S Murthy… - The Lancet …, 2024 - thelancet.com
Background Cancer is a leading cause of mortality worldwide. By 2040, over 30 million new
cancers are predicted, with the greatest cancer burden in low-income countries. In 2015, the …

Age‐specific incidence trends of 32 cancers in China, 1983 to 2032: Evidence from Cancer Incidence in Five Continents

M Hu, M Li, Y Lin, J Pei, Q Yao, L Jiang… - … Journal of Cancer, 2024 - Wiley Online Library
The long‐term incidence trends of 32 cancers in China remained unclear. Cancer statistics
for young population were often presented in aggregate, masking important heterogeneity …

Global cancer statistics: A healthy population relies on population health.

N Jokhadze, A Das, DS Dizon - CA: A Cancer Journal for …, 2024 - search.ebscohost.com
The article provides an update on global cancer statistics, revealing that 20 million people
will receive a new cancer diagnosis and nearly 10 million will die from cancer. The data is …

Design, synthesis, and biological evaluation of novel benzimidazole derivatives as anti-cervical cancer agents through PI3K/Akt/mTOR pathway and tubulin inhibition

SS Li, JJ Chen, MM Zhang, WX Wang… - European Journal of …, 2024 - Elsevier
Abstract Phosphatidylinositol 3-kinase (PI3K) is one of the most attractive therapeutic targets
for cervical cancer treatment. In this study, we designed and synthesized a series of …

An Acceptor–Donor–Acceptor Structured Nano‐Aggregate for NIR‐Triggered Interventional Photoimmunotherapy of Cervical Cancer

G Niu, X Bi, Y Kang, H Zhao, R Li, M Ding… - Advanced …, 2024 - Wiley Online Library
Compared with conventional therapies, photoimmunotherapy offers precise targeted cancer
treatment with minimal damage to healthy tissues and reduced side effects, but its efficacy …

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer

GDS Ferretti, CE Quaas, I Bertolini, A Zuccotti… - Cell Death & …, 2024 - nature.com
Pancreatic ductal adenocarcinoma (PDAC), the most prevalent type of pancreatic cancer, is
one of the deadliest forms of cancer with limited therapy options. Overexpression of the heat …

Bismuth Sulfide Nanoflowers Facilitated miR339 Delivery to Overcome Stemness and Radioresistance through Ubiquitin-Specific Peptidase 8 in Esophageal Cancer

X Zhou, F Gao, W Gao, Q Wang, X Li, X Li, W Li, J Liu… - ACS …, 2024 - ACS Publications
Despite the superior efficacy of radiotherapy in esophageal squamous cell carcinoma
(ESCC), radioresistance by cancer stem cells (CSCs) leads to recurrence, metastasis, and …

Tumor Redox‐Responsive Minimalist B/Fe Nano‐Chains for Chemodynamically Enhanced Ferroptosis and Synergistic Boron Neutron Capture Therapy

M Wang, H Hao, P Bai, J Wu, Z Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Boron neutron capture therapy (BNCT) as a binary targeted particle radiotherapy strategy
has shown potent anti‐cancer potential. However, biological barriers and restricted blood …