Clinical proton MR spectroscopy in central nervous system disorders

G Öz, JR Alger, PB Barker, R Bartha, A Bizzi, C Boesch… - Radiology, 2014 - pubs.rsna.org
A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …

Proton NMR chemical shifts and coupling constants for brain metabolites

V Govindaraju, K Young… - NMR in Biomedicine: An …, 2000 - Wiley Online Library
Proton NMR chemical shift and J‐coupling values are presented for 35 metabolites that can
be detected by in vivo or in vitro NMR studies of mammalian brain. Measurements were …

Preprocessing, analysis and quantification in single‐voxel magnetic resonance spectroscopy: experts' consensus recommendations

J Near, AD Harris, C Juchem, R Kreis… - NMR in …, 2021 - Wiley Online Library
Once an MRS dataset has been acquired, several important steps must be taken to obtain
the desired metabolite concentration measures. First, the data must be preprocessed to …

[图书][B] In vivo NMR spectroscopy: principles and techniques

RA De Graaf - 2019 - books.google.com
Presents basic concepts, experimental methodology and data acquisition, and processing
standards of in vivo NMR spectroscopy This book covers, in detail, the technical and …

Issues of spectral quality in clinical 1H‐magnetic resonance spectroscopy and a gallery of artifacts

R Kreis - NMR in Biomedicine, 2004 - Wiley Online Library
In spite of the facts that magnetic resonance spectroscopy (MRS) is applied as clinical tool in
non‐specialized institutions and that semi‐automatic acquisition and processing tools can …

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: background and experts' consensus recommendations

R Kreis, V Boer, IY Choi, C Cudalbu… - NMR in …, 2021 - Wiley Online Library
With a 40‐year history of use for in vivo studies, the terminology used to describe the
methodology and results of magnetic resonance spectroscopy (MRS) has grown …

1H MR Spectroscopy of the Brain: Absolute Quantification of Metabolites1

JFA Jansen, WH Backes, K Nicolay, ME Kooi - Radiology, 2006 - pubs.rsna.org
Hydrogen 1 (1H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations …

MR spectroscopic imaging: principles and recent advances

S Posse, R Otazo, SR Dager… - Journal of Magnetic …, 2013 - Wiley Online Library
MR spectroscopic imaging (MRSI) has become a valuable tool for quantifying metabolic
abnormalities in human brain, prostate, breast and other organs. It is used in routine clinical …

Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time 1H NMR spectra of the rat brain

J Pfeuffer, I Tkáč, SW Provencher, R Gruetter - Journal of magnetic …, 1999 - Elsevier
Localized in vivo1H NMR spectroscopy was performed with 2-ms echo time in the rat brain
at 9.4 T. Frequency domain analysis with LCModel showed that the in vivo spectra can be …

Short echo time 1H‐MRSI of the human brain at 3T with minimal chemical shift displacement errors using adiabatic refocusing pulses

TWJ Scheenen, DWJ Klomp, JP Wijnen… - … in Medicine: An …, 2008 - Wiley Online Library
The chemical shift displacement error (CSDE) is an often‐underestimated problem in slice
selection for localized proton spectroscopy at higher fields. With the proposed semi …