Early disease diagnosis relies on the sensitive detection and imaging of biomarkers. Signal
amplification is one of the most commonly used methods to improve detection sensitivity …

Procalcitonin (PCT) serves as a crucial biomarker utilized in diverse clinical contexts,
including sepsis diagnosis and emergency departments. Its applications extend to …

In this work, an intelligent and versatile electrochemical biosensor was constructed to detect
two types of biomarkers by utilizing “off-on-off” switching. Firstly, human apurinic/apyrimidinic …

Objective This study describes the development of a cost-effective and sensitive
immunosensor for rapid detection of the dengue virus (DENV) antigen in human plasma …

The robust point-of-care platform for sensitive, multiplexed, and affordable detection of
allergen-specific IgE (sIgE) is an urgent demand in component-resolved diagnostics. Here …

Nanofluidic hybrid membranes display distinct ionic current rectification (ICR) properties and
provide high surface area for immobilizing probes on the outer surface, exhibiting great …

Immunosorbent assay is one of the most popular immunological screening techniques
which has been widely used for the clinical diagnosis of alpha-fetoprotein (AFP). While …

Fe–N-doped carbon nanomaterials (Fe–N/CMs) were designed as a novel biomimetic
enzyme with excellent peroxidase-like activity to achieve high-efficient enzyme cascade …

Single-cell analysis has become increasingly important in uncovering cell heterogeneity,
which has great implications in medicine and biology for a deep understanding of cell …

On-site multi-enzymes detection and inhibitors screening are still challenging and
particularly urgent. Here, dual-channel foldable microfluidic paper (μPAD)-based parallel …