Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Neurological diseases, particularly in the context of aging, have serious impacts on quality of
life and can negatively affect bone health. The brain-bone axis is critically important for …

On the occasion of the 13th International Conference on Osteogenesis imperfecta in August
2017 an expert panel was convened to develop an international consensus paper regarding …

Following the increased awareness about the central role of the pediatric age in building
bone for life, clinicians face more than ever the necessity of assessing bone health in …

Background Spinal muscular atrophy (SMA) is an autosomal-recessive motor neuron
disease leading to dysfunction of multiple organs. SMA can impair the quality of life (QoL) of …

Both sarcopenia and osteoporosis are common geriatric diseases causing huge
socioeconomic burdens, and clinically, they often occur simultaneously. Observational …

Fractures in patients with osteogenesis imperfecta (OI) are caused by a decreased strength
of bone due to a decreased quality and quantity of bone matrix and architecture. Mutations …

X-linked hypophosphatemia (XLH) is the most common hereditary form of rickets and
deficiency of renal tubular phosphate transport in humans. XLH is caused by the inactivation …

Energy metabolism is a point of integration among the various organs and tissues of the
human body, not only in terms of consumption of energy substrates but also because it …

Cystic fibrosis (CF) is a genetic condition primarily affecting the respiratory system, with the
associated progressive lung damage and loss of function resulting in reduced lifespan …