Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …

The role of host genetics in the immune response to SARS‐CoV‐2 and COVID‐19 susceptibility and severity

IG Ovsyannikova, IH Haralambieva… - Immunological …, 2020 - Wiley Online Library
This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

J Mateus, A Grifoni, A Tarke, J Sidney, SI Ramirez… - Science, 2020 - science.org
Many unknowns exist about human immune responses to the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4+ T cells have …

[HTML][HTML] Age-related morbidity and mortality among patients with COVID-19

SJ Kang, SI Jung - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
Abstract On March 11, 2020, the World Health Organization declared coronavirus disease
(COVID-19), caused by the novel coronavirus severe acute respiratory syndrome …

Monocytes and macrophages in COVID-19: Friends and foes

S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …

[HTML][HTML] Progress and pitfalls in the quest for effective SARS-CoV-2 (COVID-19) vaccines

KL Flanagan, E Best, NW Crawford, M Giles… - Frontiers in …, 2020 - frontiersin.org
There are currently around 200 SARS-CoV-2 candidate vaccines in preclinical and clinical
trials throughout the world. The various candidates employ a range of vaccine strategies …

Role of antibody-dependent enhancement (ADE) in the virulence of SARS-CoV-2 and its mitigation strategies for the development of vaccines and immunotherapies …

K Karthik, TMA Senthilkumar… - Human vaccines & …, 2020 - Taylor & Francis
ABSTRACT Coronavirus disease-2019 (COVID-19) pandemic has become a global threat
and death tolls are increasing worldwide. The SARS-CoV-2 though shares similarities with …

Particulate alum via pickering emulsion for an enhanced COVID‐19 vaccine adjuvant

S Peng, F Cao, Y Xia, XD Gao, L Dai, J Yan… - Advanced …, 2020 - Wiley Online Library
For rapid response against the prevailing COVID‐19 (coronavirus disease 19), it is a global
imperative to exploit the immunogenicity of existing formulations for safe and efficient …

Gold Nanorod Assisted Enhanced Plasmonic Detection Scheme of COVID‐19 SARS‐CoV‐2 Spike Protein

CM Das, Y Guo, G Yang, L Kang, G Xu… - Advanced theory …, 2020 - Wiley Online Library
The beautiful interplay between light and matter can give rise to many striking physical
phenomena, surface plasmon resonance (SPR) being one of them. Plasmonic …

[HTML][HTML] An assessment on impact of COVID-19 infection in a gender specific manner

H Agrawal, N Das, S Nathani, S Saha, S Saini… - Stem cell reviews and …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by novel coronavirus Severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was first time reported in …