TGF-β signal transduction

J Massagué - Annual review of biochemistry, 1998 - annualreviews.org
The transforming growth factor β (TGF-β) family of growth factors control the development
and homeostasis of most tissues in metazoan organisms. Work over the past few years has …

[PDF][PDF] Transforming growth factor-beta in disease: the dark side of tissue repair.

WA Border, E Ruoslahti - The Journal of clinical …, 1992 - Am Soc Clin Investig
Perspectives Page 1 Perspectives Transforming Growth Factor-,B in Disease: The Dark Side of
Tissue Repair Wayne A. Border* and Erkki Ruoslahtit *Division ofNephrology, University …

Transforming growth factor βs and wound healing

S O'Kane, MWJ Ferguson - The international journal of biochemistry & cell …, 1997 - Elsevier
The Transforming Growth Factor β superfamily (TGFβ) is one of the most complex groups of
cytokines with widespread effects on many aspects of growth and development. The TGFβ …

Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system

MH Whitnall - Progress in neurobiology, 1993 - Elsevier
1. The hypothalamo-pituitary-adrenal axis (HPA) 574 1.1. Control of glucocorticoid levels
during stress 577 1.2. The diurnal rhythm of HPA activity 579 2. Roles of corticotropin …

Leydig cells: endocrine, paracrine, and autocrine regulation

JM Saez - Endocrine reviews, 1994 - academic.oup.com
THAT the testes are related to the sexual characteristics of the individual and have
reproductive power was observed at an early time in history. One of the earliest descriptions …

Anti-mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition

MFR Sowers, AD Eyvazzadeh… - The Journal of …, 2008 - academic.oup.com
Context/Objective: The objective of the study was to determine whether anti-Mullerian
hormone (AMH) and inhibin B are viable endocrine biomarkers for framing the menopause …

Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors

L Attisano, J Cárcamo, F Ventura, FMB Weis… - Cell, 1993 - cell.com
Transforming growth factor p (TGFf3) and activin each bind to pairs of membrane proteins,
known as receptor types I and II, that associate to form a signaling complex. We report that …

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

LS Mathews, WW Vale - Cell, 1991 - cell.com
Activins are involved in the regulation of multiple biological events, ranging from early
development to pituitary function. To characterize the cellular mechanisms involved in these …

Cloning of a TGFβ type I receptor that forms a heteromeric complex with the TGFβ type II receptor

P Franzen, P ten Dijke, H Ichijo, H Yamashita, P Schulz… - Cell, 1993 - cell.com
A cDNA clone encoding a 53 kd serine/threonine kinase receptor with an overall structure
similar to that of the type II receptor for transforming growth factor 9 (TGF5) was obtained …

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.

A Vassalli, MM Matzuk, HA Gardner… - Genes & …, 1994 - genesdev.cshlp.org
Inhibins and activins are dimeric growth factors of the transforming growth factor-beta
superfamily, a class of peptides that can regulate the growth and differentiation of a variety of …