Catalytic C–C bond-forming multi-component cascade or domino reactions: Pushing the boundaries of complexity in asymmetric organocatalysis

CMR Volla, I Atodiresei, M Rueping - Chemical Reviews, 2014 - ACS Publications
The construction of carbon− carbon bonds, along with the creation of stereogenic carbon
centers, continues to be an appealing and demanding area of research, and processes in …

Stereocontrolled domino reactions

H Pellissier - Chemical Reviews, 2013 - ACS Publications
A domino reaction has been defined by Tietze as a reaction involving two or more bond-
forming transformations that take place under the same reaction conditions, without adding …

Dearomative ring expansion of thiophenes by bicyclobutane insertion

H Wang, H Shao, A Das, S Dutta, HT Chan, C Daniliuc… - Science, 2023 - science.org
Skeletal ring enlargement is gaining renewed interest in synthetic chemistry and has
recently focused on insertion of one or two atoms. Strategies for heterocyclic expansion …

Recent developments in asymmetric organocatalytic domino reactions

H Pellissier - Advanced Synthesis & Catalysis, 2012 - Wiley Online Library
Since about the year 2000, the research area of asymmetric organocatalysis has grown
rapidly to become one of the most fascinating and current fields in organic chemistry. In the …

Pharmaceuticals that contain polycyclic hydrocarbon scaffolds

TP Stockdale, CM Williams - Chemical Society Reviews, 2015 - pubs.rsc.org
Numerous variations on structural motifs exist within pharmaceutical compounds that have
entered the clinic. These variations have amounted over many decades based on years of …

All-carbon quaternary stereogenic centers in acyclic systems through the creation of several C–C bonds per chemical step

I Marek, Y Minko, M Pasco, T Mejuch… - Journal of the …, 2014 - ACS Publications
In the past few decades, it has become clear that asymmetric catalysis is one of the most
powerful methods for the construction of carbon–carbon as well as carbon–heteroatom …

Enantioselective cobalt-catalyzed transformations

H Pellissier, H Clavier - Chemical reviews, 2014 - ACS Publications
1. INTRODUCTION The catalysis of organic reactions by metals still constitutes one of the
most useful and powerful tools in organic synthesis. 1 Although asymmetric synthesis is …

Total synthesis of natural products with bridged bicyclo [mn 1] ring systems via type II [5+ 2] cycloaddition

L Min, X Liu, CC Li - Accounts of Chemical Research, 2020 - ACS Publications
Conspectus Natural products containing bridged ring systems are widely identified and
show significant biological activity. The development of efficient synthesis reactions and …

Access to CF2COR-Containing Quinazolinones via Visible-Light-Induced Domino Difluoroalkylation/Cyclization of N-Cyanamide Alkenes

Y Cui, W Xu, W Yang, F Meng - Organic Letters, 2024 - ACS Publications
A green and highly efficient visible-light-induced radical cascade difluoroalkylation/
cyclization reaction of N-cyanamide alkenes has been developed. A variety of CF2COR …

Enantioselective silver-catalyzed transformations

H Pellissier - Chemical Reviews, 2016 - ACS Publications
Enantioselective Silver-Catalyzed Transformations | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted. Most …