Protein transport via the Sec translocon represents an evolutionary conserved mechanism
for delivering cytosolically-synthesized proteins to extra-cytosolic compartments. The Sec …

RNA polymerase (Pol) III transcribes small untranslated RNAs such as 5S ribosomal RNA,
transfer RNAs, and U6 small nuclear RNA. Because of the functions of these RNAs, Pol III …

The signal recognition particle (SRP) and its membrane-bound receptor (SR) deliver
membrane proteins and secretory proteins to the translocation channel in the plasma …

In all three kingdoms of life, co-translational targeting of secretory and membrane proteins to
the prokaryotic plasma membrane or eukaryotic endoplasmic reticulum is mediated by a …

Protein biogenesis is essential in all cells and initiates when a nascent polypeptide emerges
from the ribosome exit tunnel, where multiple ribosome-associated protein biogenesis …

The synthesis of secretory or integral membrane proteins can be directly coupled to their
translocation across or insertion into membranes. In co-translational targeting, the …

For targeting and integration of proteins into the mammalian endoplasmic reticulum, two
types of signals can be distinguished: those that translocate their C-terminal sequence …

Signal recognition particle (SRP) is an RNA and protein complex that exists in all domains of
life. It consists of one protein and one noncoding RNA in some bacteria. It is more complex …

Signal recognition particle (SRP), together with its receptor (SR), mediates the targeting of
ribosome-nascent chain complexes to the endoplasmic reticulum. Using protein cross …

The signal recognition particle (SRP) is a ribonucleoprotein particle essential for the
targeting of signal peptide-bearing proteins to the prokaryotic plasma membrane or the …