Prospects and challenges for cell-cultured fat as a novel food ingredient

KD Fish, NR Rubio, AJ Stout, JSK Yuen… - Trends in food science & …, 2020 - Elsevier
Background In vitro meat production has been proposed as a solution to environmental and
animal welfare issues associated with animal agriculture. While most academic work on cell …

Fabrication techniques of biomimetic scaffolds in three‐dimensional cell culture: A review

AK Badekila, S Kini, AK Jaiswal - Journal of cellular physiology, 2021 - Wiley Online Library
In the last four decades, several researchers worldwide have routinely and meticulously
exercised cell culture experiments in two‐dimensional (2D) platforms. Using traditionally …

Three-dimensional hyaluronic acid hydrogel-based models for in vitro human iPSC-derived NPC culture and differentiation

S Wu, R Xu, B Duan, P Jiang - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Human induced pluripotent stem cell-derived neural progenitor cells (hiPSC-NPCs) are
considered as a promising cell source for transplantation and have been used for organoid …

Three-dimensional bioactive hydrogel-based scaffolds for bone regeneration in implant dentistry

MB Sordi, A Cruz, MC Fredel, R Magini… - Materials Science and …, 2021 - Elsevier
Bone tissue requires a range of complex mechanisms to allow the restoration of its structure
and function. Bone healing is a signaling cascade process, involving cells secreting …

Patient-derived xenograft models of pancreatic cancer: overview and comparison with other types of models

PL Garcia, AL Miller, KJ Yoon - Cancers, 2020 - mdpi.com
Pancreatic cancer (PC) is anticipated to be second only to lung cancer as the leading cause
of cancer-related deaths in the United States by 2030. Surgery remains the only potentially …

Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

FEO Holmberg, JB Seidelin, X Yin, BE Mead… - EMBO molecular …, 2017 - embopress.org
Both the incidence and prevalence of inflammatory bowel disease (IBD) is increasing
globally; in the industrialized world up to 0.5% of the population are affected and around 4.2 …

Guide to the assessment of mature liver gene expression in stem cell-derived hepatocytes

M Zabulica, RC Srinivasan, M Vosough… - Stem cells and …, 2019 - liebertpub.com
Differentiation of stem cells to hepatocyte-like cells (HLCs) holds great promise for basic
research, drug and toxicological investigations, and clinical applications. There are currently …

Acoustic assembly of cell spheroids in disposable capillaries

Y Wu, Z Ao, B Chen, M Muhsen, M Bondesson… - …, 2018 - iopscience.iop.org
Multicellular spheroids represent a promising approach to mimic 3D tissues in vivo for
emerging applications in regenerative medicine, therapeutic screening, and drug discovery …

Perspectives on scaling production of adipose tissue for food applications

JSK Yuen Jr, AJ Stout, NS Kawecki, SM Letcher… - Biomaterials, 2022 - Elsevier
With rising global demand for food proteins and significant environmental impact associated
with conventional animal agriculture, it is important to develop sustainable alternatives to …

An injectable non-cross-linked hyaluronic-acid gel containing therapeutic spheroids of human adipose-derived stem cells

J Feng, K Mineda, SH Wu, T Mashiko, K Doi, S Kuno… - Scientific Reports, 2017 - nature.com
For chronic wounds, the delivery of stem cells in spheroidal structures can enhance graft
survival and stem cell potency. We describe an easy method for the 3D culture of adipose …