[HTML][HTML] EMT, cancer stem cells and autophagy; The three main axes of metastasis
G Babaei, SGG Aziz, NZZ Jaghi - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Epithelial-mesenchymal transition (EMT) and Cancer stem-like cells (CSCs) are major
factors contributing to the metastasis of cancer cells. Consequently, the signaling pathways …
factors contributing to the metastasis of cancer cells. Consequently, the signaling pathways …
New and emerging targeted therapies for advanced breast cancer
KH Lau, AM Tan, Y Shi - International journal of molecular sciences, 2022 - mdpi.com
In the United States, breast cancer is among the most frequently diagnosed cancers in
women. Breast cancer is classified into four major subtypes: human epidermal growth factor …
women. Breast cancer is classified into four major subtypes: human epidermal growth factor …
Pathological implication of protein post-translational modifications in cancer
S Pan, R Chen - Molecular aspects of medicine, 2022 - Elsevier
Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …
How the Warburg effect supports aggressiveness and drug resistance of cancer cells?
P Icard, S Shulman, D Farhat, JM Steyaert… - Drug Resistance …, 2018 - Elsevier
Cancer cells employ both conventional oxidative metabolism and glycolytic anaerobic
metabolism. However, their proliferation is marked by a shift towards increasing glycolytic …
metabolism. However, their proliferation is marked by a shift towards increasing glycolytic …
Flavonoids against the Warburg phenotype—Concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism
The Warburg effect is characterised by increased glucose uptake and lactate secretion in
cancer cells resulting from metabolic transformation in tumour tissue. The corresponding …
cancer cells resulting from metabolic transformation in tumour tissue. The corresponding …
Fumarate hydratase in cancer: A multifaceted tumour suppressor
Cancer is now considered a multifactorial disorder with different aetiologies and outcomes.
Yet, all cancers share some common molecular features. Among these, the reprogramming …
Yet, all cancers share some common molecular features. Among these, the reprogramming …
Role of metabolic reprogramming in epithelial–mesenchymal transition (EMT)
Activation of epithelial–mesenchymal transition (EMT) is thought to be an essential step for
cancer metastasis. Tumor cells undergo EMT in response to a diverse range of extra-and …
cancer metastasis. Tumor cells undergo EMT in response to a diverse range of extra-and …
AMPK: a balancer of the renin–angiotensin system
The renin–angiotensin system (RAS) is undisputedly well-studied as one of the oldest and
most critical regulators for arterial blood pressure, fluid volume, as well as renal function. In …
most critical regulators for arterial blood pressure, fluid volume, as well as renal function. In …
Analysis of lncRNA-associated ceRNA network reveals potential lncRNA biomarkers in human colon adenocarcinoma
Z Zhang, W Qian, S Wang, D Ji, Q Wang, J Li… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Long non-coding RNAs (lncRNAs) acting as competing
endogenous RNAs (ceRNAs) play significant roles in the development of tumors, but the …
endogenous RNAs (ceRNAs) play significant roles in the development of tumors, but the …
Unraveling the anticancer effect of curcumin and resveratrol
AR Pavan, GDB Silva, DH Jornada, DE Chiba… - Nutrients, 2016 - mdpi.com
Resveratrol and curcumin are natural products with important therapeutic properties useful
to treat several human diseases, including cancer. In the last years, the number of studies …
to treat several human diseases, including cancer. In the last years, the number of studies …