Heavy metal associated health hazards: An interplay of oxidative stress and signal transduction

JG Paithankar, S Saini, S Dwivedi, A Sharma… - Chemosphere, 2021 - Elsevier
Heavy metal-induced cellular and organismal toxicity have become a major health concern
in biomedical science. Indiscriminate use of heavy metals in different sectors, such as …

Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms

M Gade, N Comfort, DB Re - Environmental research, 2021 - Elsevier
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …

In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury

F Qian, Y Han, Z Han, D Zhang, L Zhang, G Zhao, S Li… - Biomaterials, 2021 - Elsevier
Traumatic brain injury (TBI) generates excess reactive oxygen species (ROS), which can
exacerbate secondary injury and result in disability and death. Secondary injury cascades …

Neural stem cell therapy in conjunction with curcumin loaded in niosomal nanoparticles enhanced recovery from traumatic brain injury

A Narouiepour, A Ebrahimzadeh-Bideskan… - Scientific Reports, 2022 - nature.com
Despite a great amount of effort, there is still a need for reliable treatments of traumatic brain
injury (TBI). Recently, stem cell therapy has emerged as a new avenue to address neuronal …

Counteracting arsenic toxicity: curcumin to the rescue?

A Bahrami, T Sathyapalan, SA Moallem… - Journal of hazardous …, 2020 - Elsevier
Arsenicosis leads to various irreversible damages in several organs and is considered to be
a carcinogen. The effects of chronic arsenic poisoning are a result of an imbalance between …

Roles of neural stem cells in the repair of peripheral nerve injury

C Wang, C Lu, J Peng, C Hu… - Neural regeneration …, 2017 - journals.lww.com
Currently, researchers are using neural stem cell transplantation to promote regeneration
after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve …

Role of curcumin and its nanoformulations in the treatment of neurological diseases through the effects on stem cells

N Sabouni, HZ Marzouni, S Palizban… - Journal of Drug …, 2023 - Taylor & Francis
Curcumin from turmeric is a natural phenolic compound with a promising potential to
regulate fundamental processes involved in neurological diseases, including inflammation …

Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: a review of molecular pathways

P Joshi, A Bisht, S Joshi, D Semwal… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin, isolated from turmeric (Curcuma longa L.) is one of the broadly studied
phytomolecule owing to its strong antioxidant and anti‐inflammatory potential and has been …

The protective effect of natural or chemical compounds against arsenic-induced neurotoxicity: Cellular and molecular mechanisms

M Shayan, S Barangi, H Hosseinzadeh… - Food and Chemical …, 2023 - Elsevier
Arsenic is a notorious metalloid that exists in the earth's crust and is considered toxic for
humans and the environment. Both cancerous and non-cancerous complications are …

[HTML][HTML] Protective effects of curcumin on ATO-induced nephrotoxicity in ducks in relation to suppressed autophagy, apoptosis and dyslipidemia by regulating …

S Wu, W Yu, X Jiang, R Huang, X Zhang, J Lan… - Ecotoxicology and …, 2021 - Elsevier
Arsenic trioxide (ATO) has been known as common environmental pollution, and is deemed
to a threat to global public health. Curcumin (Cur) is a phytoconstituent, which has been …