Unraveling mosquito metabolism with mass spectrometry-based metabolomics

TD Horvath, S Dagan, PY Scaraffia - Trends in parasitology, 2021 - cell.com
Nearly half a million people die annually due to mosquito-borne diseases. Despite
aggressive mosquito population-control efforts, current strategies are limited in their ability to …

Genetic toolbox approaches in mosquitoes

O Riabinina, M Quinn… - Cold Spring Harbor …, 2022 - cshprotocols.cshlp.org
Mosquitoes are fascinating and diverse study organisms that are rapidly becoming
genetically tractable. Here, we review the latest and most commonly used approaches to …

CRISPR/Cas9 mediates efficient site‐specific mutagenesis of the odorant receptor co‐receptor (Orco) in the malaria vector Anopheles sinensis

Y Wang, X He, L Qiao, Z Yu, B Chen… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND Anopheles sinensis is the most widely distributed mosquito species and is
the main transmitter of Plasmodium vivax malaria in China. Most previous research has …

Mosquito metallomics reveal copper and iron as critical factors for Plasmodium infection

K Maya-Maldonado, V Cardoso-Jaime… - PLoS neglected …, 2021 - journals.plos.org
Iron and copper chelation restricts Plasmodium growth in vitro and in mammalian hosts. The
parasite alters metal homeostasis in red blood cells to its favor, for example metabolizing …

Genetics tools for corpora allata specific gene expression in Aedes aegypti mosquitoes

M Nouzova, MJ Edwards, M DeGennaro, D Leyva… - Scientific Reports, 2022 - nature.com
Juvenile hormone (JH) is synthesized by the corpora allata (CA) and controls development
and reproduction in insects. Therefore, achieving tissue-specific expression of transgenes in …

Site-Directed φC31-Mediated Integration and Cassette Exchange in Anopheles Vectors of Malaria.

A Adolfi, A Lynd, GJ Lycett… - Journal of Visualized …, 2021 - escholarship.org
Functional genomic analysis and related strategies for genetic control of malaria rely on
validated and reproducible methods to accurately modify the genome of Anopheles …

Leaning into the bite: the piRNA pathway as an exemplar for the genetic engineering need in mosquitoes

VM Macias, U Palatini, M Bonizzoni… - Frontiers in Cellular and …, 2021 - frontiersin.org
The piRNA pathway is a specialized small RNA interference that in mosquitoes is
mechanistically distant from analogous biology in the Drosophila model. Current genetic …

[PDF][PDF] The mosquito and malaria: Would mosquito control alone eliminate the disease?

W Takken - Mosquitopia, 2021 - library.oapen.org
110 Willem Takken zygote, which subsequently develops into an oocyte. Next, oocytes
migrate to the interior wall of the mosquito's midgut where they grow out into oocysts in …

Theme and variation in the development of insect mouthparts

DR Angelini, FW Smith - Insect Mouthparts: Form, Function, Development …, 2019 - Springer
Insect mouthparts are serially homologous appendages. As such, their development and
evolution are nonindependent. Arthropod appendages share similarities in their …

Characterizing insecticide resistance mechanisms in mosquitoes using genetic modification and a rapid automated larval resistance detection assay

B Poulton - 2021 - archive.lstmed.ac.uk
Insecticide resistance is a threat to malaria and arbovirus control programmes targeting
mosquito vectors. Integrated control programmes which include control of larval stages are …