Abstract Purpose of Review For many years, exercise was controversial in multiple sclerosis
(MS) and thought to exacerbate symptoms and fatigue. However, having been found to be …

Background A moderate to high level of physical activity, including regular exercise,
represents an established behavioral and rehabilitative approach for persons with multiple …

Background Lower-limb functional capacity is impaired in most people with multiple
sclerosis (PwMS). Reductions in lower-extremity muscle mechanical function (eg, muscle …

Introduction: Mobility disability is one of the most widespread and impactful consequences of
multiple sclerosis (MS). Disease modifying drugs (DMDs) may delay the progression of …

Despite important efforts to solve the clinico-radiological paradox, correlation between
lesion load and physical disability in patients with multiple sclerosis remains modest. One …

Objectives Diffusion tensor imaging (DTI) is sensitive technique to detect widespread
changes in water diffusivity in the normal‐appearing white matter (NAWM) that appears …

Myelin-sensitive MRI such as magnetization transfer imaging has been widely used in
multiple sclerosis. The influence of methodology and differences in disease subtype on …

Impaired locomotion is a frequent and major source of disability in patients with neurological
conditions. Different neuroimaging methods have been used to understand the brain …

Background Neurodegeneration is an inevitable consequence of multiple sclerosis (MS)
leading to impaired neuromuscular function, especially of the lower extremities. Whilst …

Objectives Investigate whether asymmetrical corticospinal excitability exists in Multiple
Sclerosis (MS) and its association with MS symptoms. Methods Bilateral resting and active …