The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …

The past decade has witnessed groundbreaking advances in the field of microbiome
research. An area where immense implications of the microbiome have been demonstrated …

This is the first prospective study of the effects of human gut microbiota and metabolites on
immune checkpoint inhibitor (ICT) response in metastatic melanoma patients. Whereas …

Fatty acids and lipids, which are major and essential constituents of all plant cells, not only
provide structural integrity and energy for various metabolic processes but can also function …

Epigenetic changes such as DNA methylation and histone methylation and acetylation alter
gene expression at the level of transcription by upregulating, downregulating, or silencing …

The multifactorial nature of Alzheimer's disease (AD) is a reason for the lack of effective
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …

The aqueous cashew leaves extract obtained was investigated for the preparation of gold
nanoparticle (AuNPs). The obtained AuNPs were characterized by UV–Visible …

In the development of cancer chemotherapy, besides the discovery of new anticancer drugs,
a variety of nanocarrier systems for the delivery of previously developed and new …

Caloric restriction, be it constant or intermittent, is reputed to have health-promoting and
lifespan-extending effects. Caloric restriction mimetics (CRMs) are compounds that mimic …

Phytochemical and bioactivity analyses of pistachio hulls revealed the presence of
anacardic acids (3198 mg/100 g), fatty acids (1500 mg/100 g), and phytosterols (192 mg/100 …