Five years of GWAS discovery
The past five years have seen many scientific and biological discoveries made through the
experimental design of genome-wide association studies (GWASs). These studies were …
experimental design of genome-wide association studies (GWASs). These studies were …
Bioelectrical signals as emerging biometrics: Issues and challenges
This paper presents the effectiveness of bioelectrical signals such as the electrocardiogram
(ECG) and the electroencephalogram (EEG) for biometric applications. Studies show that …
(ECG) and the electroencephalogram (EEG) for biometric applications. Studies show that …
Epidemiology and genetics of sudden cardiac death
R Deo, CM Albert - Circulation, 2012 - Am Heart Assoc
Sudden cardiac death (SCD) generally refers to an unexpected death from a cardiovascular
cause in a person with or without preexisting heart disease. The specificity of this definition …
cause in a person with or without preexisting heart disease. The specificity of this definition …
Genome partitioning of genetic variation for complex traits using common SNPs
J Yang, TA Manolio, LR Pasquale, E Boerwinkle… - Nature …, 2011 - nature.com
We estimate and partition genetic variation for height, body mass index (BMI), von
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …
Several common variants modulate heart rate, PR interval and QRS duration
Electrocardiographic measures are indicative of the function of the cardiac conduction
system. To search for sequence variants that modulate heart rate, PR interval and QRS …
system. To search for sequence variants that modulate heart rate, PR interval and QRS …
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
M Den Hoed, M Eijgelsheim, T Esko, BJJM Brundel… - Nature …, 2013 - nature.com
Elevated resting heart rate is associated with greater risk of cardiovascular disease and
mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 …
mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 …
[HTML][HTML] Pacemaker channel dysfunction in a patient with sinus node disease
E Schulze-Bahr, A Neu, P Friederich… - The Journal of …, 2003 - Am Soc Clin Investig
The cardiac pacemaker current I f is a major determinant of diastolic depolarization in sinus
nodal cells and has a key role in heartbeat generation. Therefore, we hypothesized that …
nodal cells and has a key role in heartbeat generation. Therefore, we hypothesized that …
Genome-and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk
Background—ECG QRS duration, a measure of cardiac intraventricular conduction, varies≈
2-fold in individuals without cardiac disease. Slow conduction may promote re-entrant …
2-fold in individuals without cardiac disease. Slow conduction may promote re-entrant …
Genome-wide association analysis identifies multiple loci related to resting heart rate
M Eijgelsheim, C Newton-Cheh… - Human molecular …, 2010 - academic.oup.com
Higher resting heart rate is associated with increased cardiovascular disease and mortality
risk. Though heritable factors play a substantial role in population variation, little is known …
risk. Though heritable factors play a substantial role in population variation, little is known …
[HTML][HTML] Evaluation of electrocardiogram for biometric authentication
This paper presents an evaluation of a new biometric electrocardiogram (ECG) for individual
authentication. We report the potential of ECG as a biometric and address the research …
authentication. We report the potential of ECG as a biometric and address the research …