Biological effects of human exposure to environmental cadmium
Cadmium (Cd) is a toxic metal for the human organism and for all ecosystems. Cd is
naturally found at low levels; however, higher amounts of Cd in the environment result from …
naturally found at low levels; however, higher amounts of Cd in the environment result from …
Selenoproteins and tRNA-Sec: regulators of cancer redox homeostasis
In the past two decades significant progress has been made in uncovering the biological
function of selenium. Selenium, an essential trace element, is required for the biogenesis of …
function of selenium. Selenium, an essential trace element, is required for the biogenesis of …
Thioredoxin 1 and Thioredoxin Reductase 1 Redox System Is Dysregulated in Neutrophils of Subjects with Autism: In Vitro Effects of Environmental Toxicant …
Autism spectrum disorder (ASD) is a complex developmental disorder in children that results
in abnormal communicative and verbal behaviors. Exposure to heavy metals plays a …
in abnormal communicative and verbal behaviors. Exposure to heavy metals plays a …
Study of the magnesium comenate structure, its neuroprotective and stress-protective activity
S Kozin, A Kravtsov, L Ivashchenko… - International Journal of …, 2023 - mdpi.com
The crystal structure and the biological activity of a new coordination compound of
magnesium ions with comenic acid, magnesium comenate, was characterized and studied …
magnesium ions with comenic acid, magnesium comenate, was characterized and studied …
Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway
S Gao, Q Cheng, Y Hu, X Fan, C Liang, C Niu… - Molecular and Cellular …, 2024 - Springer
This study aimed to explore the role of melatonin in oxidative stress-induced injury on retinal
ganglion cells and the underlying mechanisms. The immortalized RGC-5 cells were treated …
ganglion cells and the underlying mechanisms. The immortalized RGC-5 cells were treated …
Disruption of Bacterial Thiol-Dependent Redox Homeostasis by Magnolol and Honokiol as an Antibacterial Strategy
Y Ouyang, X Tang, Y Zhao, X Zuo, X Ren, J Wang… - Antioxidants, 2023 - mdpi.com
Some traditional Chinese medicines (TCMs) possess various redox-regulation properties,
but whether the redox regulation contributes to antibacterial mechanisms is not known …
but whether the redox regulation contributes to antibacterial mechanisms is not known …
Auranofin Modulates Thioredoxin Reductase/Nrf2 Signaling in Peripheral Immune Cells and the CNS in a Mouse Model of Relapsing–Remitting EAE
Multiple sclerosis (MS) is one of the most prevalent chronic inflammatory autoimmune
diseases. It causes the demyelination of neurons and the subsequent degeneration of the …
diseases. It causes the demyelination of neurons and the subsequent degeneration of the …
Icaritin greatly attenuates β‐amyloid‐induced toxicity in vivo
L Li, Z Wei, Y Tang, M Jin, H Yao, X Li… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims The accumulation and deposition of β‐amyloid (Aβ) has always been considered a
major pathological feature of Alzheimer's disease (AD). The latest and mainstream amyloid …
major pathological feature of Alzheimer's disease (AD). The latest and mainstream amyloid …
Retinoic acid has neuroprotective effects by modulating thioredoxin in ischemic brain damage and glutamate-exposed neurons
JB Kang, PO Koh - Neuroscience, 2023 - Elsevier
Ischemic stroke is a neurological disorder that causes pathological changes by increasing
oxidative stress. Retinoic acid is one of the metabolites of vitamin A. It regulates oxidative …
oxidative stress. Retinoic acid is one of the metabolites of vitamin A. It regulates oxidative …
Antiproliferative, antimigratory, and apoptotic effects of diffractaic and vulpinic acids as thioredoxin reductase 1 inhibitors on cervical cancer
Cervical cancer is among the most frequently observed cancer types in females. New
therapeutic targets are needed because of the side impacts of existing cancer drugs and the …
therapeutic targets are needed because of the side impacts of existing cancer drugs and the …