The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the
ability to induce non-specific cross-protection against pathogens that might be unrelated to …

Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an
essential element of bacterial biology. Efforts to understand the Mycobacterium tuberculosis …

While a third of the world carries the burden of tuberculosis, disease control has been
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …

Tuberculosis (TB) remains the deadliest infectious disease, and the widely used Bacillus
Calmette–Guérin (BCG) vaccine fails to curb the epidemic. An improved vaccination strategy …

Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis
(TB), but it confers incomplete and variable protection against pulmonary TB in humans and …

The role of Igs in natural protection against infection by Mycobacterium tuberculosis (Mtb),
the causative agent of TB, is controversial. Although passive immunization with mAbs …

Mycobacterium tuberculosis (Mtb) exposure drives antibody responses, but whether patients
with active tuberculosis elicit protective antibodies, and against which antigens, is still …

Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death
worldwide caused by a single infectious agent; 1.6 million tuberculosis-related deaths were …

B-cells not only produce immunoglobulins and present antigens to T-cells, but also
additional key roles in the immune system. Current knowledge on the role of B-cells in …

Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), remains the
leading cause of death worldwide from a single infectious pathogen. Mtb is a paradigmatic …