The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk
K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …
Unraveling the Link between Olfactory Deficits and Neuropsychiatric Disorders
Smell loss has caught public attention during the recent COVID-19 pandemic. Research on
olfactory function in health and disease gains new momentum. Smell deficits have long …
olfactory function in health and disease gains new momentum. Smell deficits have long …
[HTML][HTML] Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression
MR Duggan, GT Gomez, CM Joynes, M Bilgel… - Brain, Behavior, and …, 2024 - Elsevier
While immune function is known to play a mechanistic role in Alzheimer's disease (AD),
whether immune proteins in peripheral circulation influence the rate of amyloid-β (Aβ) …
whether immune proteins in peripheral circulation influence the rate of amyloid-β (Aβ) …
[HTML][HTML] Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells–Implications for Alzheimer's disease
Constituents of air pollution, the ultrafine particles (UFP) with a diameter of≤ 0.1 μm, are
considerably related to traffic emissions. Several studies link air pollution to Alzheimer's …
considerably related to traffic emissions. Several studies link air pollution to Alzheimer's …
[HTML][HTML] Exposure to urban particulate matter alters responses of olfactory mucosal cells to SARS-CoV-2 infection
MA Shahbaz, S Kuivanen, L Mussalo, AM Afonin… - Environmental …, 2024 - Elsevier
Respiratory viruses have a significant impact on health, as highlighted by the COVID-19
pandemic. Exposure to air pollution can contribute to viral susceptibility and be associated …
pandemic. Exposure to air pollution can contribute to viral susceptibility and be associated …
Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders
Smell deficits and neurobiological changes in the olfactory bulb (OB) and olfactory
epithelium (OE) have been observed in schizophrenia and related disorders. The OE is the …
epithelium (OE) have been observed in schizophrenia and related disorders. The OE is the …
Neuropathological stage‐dependent proteome mapping of the olfactory tract in Alzheimer's disease: From early olfactory‐related omics signatures to computational …
P Cartas‐Cejudo, A Cortés, M Lachén‐Montes… - Brain …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia, characterized by an early
olfactory dysfunction, progressive memory loss, and behavioral deterioration. Albeit …
olfactory dysfunction, progressive memory loss, and behavioral deterioration. Albeit …
A review and analysis of key biomarkers in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects over 50
million elderly individuals worldwide. Although the pathogenesis of AD is not fully …
million elderly individuals worldwide. Although the pathogenesis of AD is not fully …
Olfactory neuroepithelium-derived cellular models to study neurological and psychiatric disorders
K Yang, OV Evgrafov - Frontiers in Neuroscience, 2023 - frontiersin.org
Neurodevelopment is a spatially and temporally regulated process that occurs mostly during
the embryonic and fetal stages. Given the sophistication of the nervous system, particularly …
the embryonic and fetal stages. Given the sophistication of the nervous system, particularly …
Alzheimer's proteinopathy in olfactory neuroepithelium from persistent olfactory impairment SARS-CoV-2 patients
CAA Grosso, R Pieruzzini, C Rodriguez, M Gil… - Authorea …, 2024 - techrxiv.org
Persistent olfactory impairment (POI) and dysgeusia are lingering symptoms following
recovery from Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. These …
recovery from Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. These …