Recent experimental evidence on patients with disorders of consciousness revealed that
observing brain-heart interactions helps to detect residual consciousness, even in patients …

Since the operative definition given by CWJ Granger of an idea expressed by N. Wiener, the
Wiener-Granger causality (WGC) has been one of the most relevant concepts exploited by …

The human organism comprises various physiological and organ systems, each with its own
structural organization and functional complexity, leading to complex, transient, fluctuating …

We systematically study how diverse physiologic systems in the human organism
dynamically interact and collectively behave to produce distinct physiologic states and …

Entropy measures are widely applied to quantify the complexity of dynamical systems in
diverse fields. However, the practical application of entropy methods is challenging, due to …

Despite the vast progress and achievements in systems biology and integrative physiology
in the last decades, there is still a significant gap in understanding the mechanisms through …

Background The choice of EEG reference has been widely studied. However, the choice of
the most appropriate re-referencing for EEG data is still debated. Moreover, the role of EEG …

Manual scoring of sleep stages from polysomnography (PSG) records is essential to
understand the sleep quality and architecture. Since the PSG requires specialized …

The study of functional brain–heart interplay has provided meaningful insights in cardiology
and neuroscience. Regarding biosignal processing, this interplay involves predominantly …

Skeletal muscle activity is continuously modulated across physiologic states to provide
coordination, flexibility and responsiveness to body tasks and external inputs. Despite the …