Pre‐B‐cell leukaemia transcription factor (PBX) proteins are a subfamily of evolutionarily
conserved, atypical homeodomain transcription factors that belong to the superfamily of …

The HOX and PBX gene families encode transcription factors that have key roles in
establishing the identity of cells and tissues in early development. Over the last 20 years it …

Cancer-associated fibroblasts (CAFs) play a pivotal role in regulating tumour progression.
Therefore, understanding how CAFs communicate with hepatocellular carcinoma (HCC) is …

Background Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor of
the head and neck. LSCC patients have seriously impaired vocal, respiratory, and …

Extracellular vesicles (EVs) are microvesicles secreted from various cell types. We aimed to
discover a new biomarker for high Gleason score (GS) prostate cancer (PCa) in urinary EVs …

DNA shape adds specificity to sequence motifs but has not been explored systematically
outside this context. We hypothesized that DNA-binding proteins (DBPs) preferentially …

The recent and exciting discovery of germline HOXB13 mutations in familial prostate cancer
has brought HOX signaling to the forefront of prostate cancer research. An enhanced …

Chemoresistance is a leading obstacle in effective management of advanced prostate
cancer (PCa). A better understanding of the molecular mechanisms involved in PCa …

Angiotensin II type 1 receptor-associated protein (ATRAP) is widely expressed in different
tissues and organs, although its mechanistic role in breast cancer remains unclear. Here, we …

Pre-B-cell leukemia transcription factor (PBX) proteins have important roles in the
development of numerous organs. To date, four members of the PBX family have been …