The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …

Endometrial cancer is the most common type of cancer of the female reproductive tract.
Although prognosis is generally good for patients with low-grade and early-stage diseases …

Prostate cancer (PCa) is the most commonly diagnosed malignancy in men and the second
leading cause of cancer‐related death in industrialized countries. Epidemiologic evidence …

Recent studies have highlighted palmitoylation, a novel protein post-translational
modification, as a key player in various signaling pathways that contribute to tumorigenesis …

Endometrial cancer is often characterized by PI3K/AKT pathway deregulation. Recently it
has been suggested that SGK1, a serine/threonine protein kinase that shares structural and …

The biguanide drug metformin is widely used in type 2 diabetes mellitus therapy, due to its
ability to decrease serum glucose levels, mainly by reducing hepatic gluconeogenesis and …

The liver is an immunologically tolerant organ and a common site of distant metastasis for
various cancers. The expression levels of glucose-regulated protein 78 (GRP78) have been …

Simple Summary Ovarian cancer (OVCA) is a fatal gynecological disease for which there is
no early detection test. Glucose-regulated protein 78 (GRP78), a protein marker of stress …

Licochalcone A (LicA), a natural compound extracted from licorice root, has been shown to
exert a variety of anticancer activities. Whether LicA has such effects on endometrial cancer …

Multiple lines of evidence suggest that metformin, an antidiabetic drug, exerts anti-
tumorigenic effects in different types of cancer. Metformin has been reported to affect cancer …