Pineapple has been used as part of traditional folk medicine since ancient times and it
continues to be present in various herbal preparations. Bromelain is a complex mixture of …

The medicinal qualities of pineapple are recognized in many traditions in South America,
China and Southeast Asia. These qualities are attributed to bromelain, a 95%-mixture of …

Chemoprevention impels the pursuit for either single targeted or cocktail of multi-targeted
agents. Bromelain, potential agent in this regard, is a pharmacologically active compound …

Abstract Stem bromelain (EC 3.4. 22.32) is a major cysteine proteinase, isolated from
pineapple (Ananas comosus) stem. Its main medicinal use is recognized as digestive, in …

Bromelain is a pharmacologically active compound, present in stems and immature fruits of
pineapples (Ananas cosmosus), which has been shown to have anti-edematous, anti …

Scope Colorectal cancer is an important health problem across the world. Here, we
investigated the possible antiproliferative/proapoptotic effects of bromelain (from the …

Background Bromelain is a pineapple stem extract with a variety of therapeutic benefits
arising from interaction with a number of different biological processes. Several preclinical …

Background Bromelain and N-acetylcysteine are two natural, sulfhydryl-containing
compounds with good safety profiles which have been investigated for their benefits and …

Cholangiocarcinoma (CC) worldwide is the most common biliary malignancy with poor
prognostic value and new systemic treatments are desirable. Plant extracts like bromelain …

Background Bromelain, which is a cysteine endopeptidase commonly found in pineapple
stems, has been investigated as a potential anti-cancer agent for the treatment of breast …