Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …

During the last decades a large number of flavin-dependent monooxygenases have been
isolated and studied. This has revealed that flavoprotein monooxygenases are able to …

Enzymes are very efficient catalysts that are essential for the functioning of living organisms.
The low efficiency of biocatalysts produced de novo relative to those that have evolved …

Monensin A is a prototypical natural polyether polyketide antibiotic. It acts by binding a metal
cation and facilitating its transport across the cell membrane. Biosynthesis of monensin A …

Abstract Baeyer–Villiger monooxygenases (BVMOs) are flavoenzymes that catalyze a
remarkably wide variety of oxidative reactions such as regio‐and enantioselective Baeyer …

Oxygenases, which catalyze the reductive activation of O2 and incorporation of oxygen
atoms into substrates, are widely distributed in aerobes. They function by switching the …

Flavoprotein monooxygenases reduce flavins, speed their reaction with oxygen, and
stabilize a C4a-oxygen adduct long enough to use this reactive species to transfer an …

Carr− Purcell− Meiboom− Gill (CPMG) relaxation measurements employing trains of 180°
pulses with variable pulse spacing provide valuable information about systems undergoing …

Many flavoenzymes catalyze hydroxylation of aromatic compounds especially phenolic
compounds have been isolated and characterized. These enzymes can be classified as …

Abstract The transformation of 4-hydroxybenzoate (4-HBA) to protocatechuate (PCA) is
catalyzed by flavoprotein oxygenases known as para-hydroxybenzoate-3-hydroxylases …