The epidemiology of Chagas disease in the Americas

ZM Cucunubá, SA Gutiérrez-Romero… - The Lancet Regional …, 2024 - thelancet.com
Chagas disease is a complex parasitic zoonosis that still threatens public health across the
Americas. Initiatives to control Trypanosoma cruzi transmission via blood transfusion and …

Clinical features of Chagas disease progression and severity

MCP Nunes, C Bern, EH Clark, AL Teixeira… - The Lancet Regional …, 2024 - thelancet.com
Chagas disease, the most common form of nonischaemic cardiomyopathy globally, is one of
the leading causes of morbidity and mortality in Latin America. Chagas cardiomyopathy has …

Biogeographic Perspectives on Human Genetic Diversification

T Hünemeier - Molecular Biology and Evolution, 2024 - academic.oup.com
Modern humans originated in Africa 300,000 yr ago, and before leaving their continent of
origin, they underwent a process of intense diversification involving complex demographic …

Adipose development is consistent across hunter–gatherers and diverges from western references

JV Hackman, BC Campbell… - … of the Royal …, 2024 - royalsocietypublishing.org
Despite agreement that humans have evolved to be unusually fat primates, adipose
patterning among hunter–gatherers has received little empirical consideration. Here we …

Local genetic adaptation to habitat in wild chimpanzees

HJ Ostridge, C Fontsere, E Lizano, DC Soto… - …, 2024 - pmc.ncbi.nlm.nih.gov
How populations adapt to their environment is a fundamental question in biology. Yet we
know surprisingly little about this process, especially for endangered species such as non …

[HTML][HTML] Human genetic determinants of COVID-19 in Brazil: challenges and future plans

BS Fam, MF Feira, NA Cadore, R Sbruzzi… - … and Molecular Biology, 2024 - SciELO Brasil
COVID-19 pandemic represented a worldwide major challenge in different areas, and efforts
undertaken by the scientific community led to the understanding of some of the genetic …

Amazon severe drought in 2023 triggered surface water loss

CM Souza, J Marengo, B Ferreira… - Environmental …, 2024 - iopscience.iop.org
The Amazon underwent a severe austral springtime drought attributed to the onset of El
Niño in 2023 and the warmer North Atlantic, Indian, and North Pacific Oceans. The Amazon …

Genetic associations with disease in populations with Indigenous American ancestries

L Vicuña - Genetics and Molecular Biology, 2024 - SciELO Brasil
The genetic architecture of complex diseases affecting populations with Indigenous
American ancestries is poorly understood due to their underrepresentation in genomics …

Uncovering Disease-Related Polymorphisms through Correlations between SNP Frequencies, Population and Epidemiological Data

SMD Reis, CA Bugs, JAB Chies, AD Cañedo - BioMedInformatics, 2023 - mdpi.com
Background: According to GWAS, which analyzes large amounts of DNA variants in case-
control strategies, the genetic differences between two human individuals do not exceed …

CaracterÃsticas epidemiológicas, clÃnico-laboratoriais e tratamento de pacientes com doenà § a de Chagas aguda em Santaré m (Pará)

HR Esper - teses.usp.br
A complexidade do ciclo da Doenà § a de Chagas na Regiã o Norte favorece
transmissões persistentes do Trypanosoma cruzi ao ser humano. Considerando-se o …