We report a systematic review and meta-analysis of studies that assessed the
antinociceptive efficacy of cannabinoids, cannabis-based medicines, and endocannabinoid …

The preclinical research community faces an ever-expanding corpus of biomedical
literature, making it challenging to keep abreast with the latest findings. This hampers …

Background Despite the increasing knowledge of the etiology of neuropathic pain, this type
of chronic pain is resistant to available analgesics in approximately 50% of patients and …

The President of the International Association for the Study of Pain established a task force
on cannabis and cannabinoid analgesia to systematically examine the evidence on (1) …

Meta-analytic techniques have been widely used to synthesize data from animal models of
human diseases and conditions, but these analyses often face two statistical challenges due …

Large variability in the individual response to even the most-efficacious pain treatments is
observed clinically, which has led to calls for a more personalized, tailored approach to …

One of the most relevant dose-limiting adverse effects of platinum drugs is the development
of a sensory peripheral neuropathy that highly impairs the patients' quality of life. Nowadays …

Background The demand for high-quality systematic literature reviews (SRs) for evidence-
based medical decision-making is growing. SRs are costly and require the scarce resource …

Peripheral neuropathy is one of the most common, dose limiting, and long-lasting disabling
adverse events of chemotherapy treatment. Unfortunately, no treatment has proven efficacy …

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose limiting, and long-
lasting side effect of chemotherapy treatment. Unfortunately, no treatment has proven …