Abstract Background Auger electrons (AEs) are very low energy electrons that are emitted
by radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I …

Breast cancer affects approximately 1 in 8 women, and it is estimated that over 246,660
women in the USA will be diagnosed with breast cancer in 2016. Breast cancer mortality has …

The EGFR-or ErbB-family of receptor tyrosine kinases consists of EGFR/ErbB1,
ErbB2/HER2, ErbB3/HER3 and ErbB4/HER4. Receptor activation and downstream …

Introduction: Breast cancer subtypes are currently defined by a combination of morphologic,
genomic, and proteomic characteristics. These subtypes provide a molecular portrait of the …

An increasing number of tumors, including breast cancer, overexpress proteins of the
epidermal growth factor receptor (EGFR) family. The interaction between family members …

Epidermal growth factor receptor (EGFR), also known as ErbB-1/HER-1, plays a key role in
the regulation of the cell proliferation, migration, differentiation, and survival. Since the …

Metastasis is the main cause of death in many cancers including colorectal cancer (CRC);
however, the underlying mechanisms responsible for metastatic progression remain largely …

Intracellular localization has been reported for over three‐quarters of receptor tyrosine
kinase (RTK) families in response to environmental stimuli. Internalized RTK may bind to …

Folic acid (FA) has traditionally been associated with prevention of neural tube defects; more
recent work suggests that it may also be involved in in the prevention of adult onset …

Abstract STING (ST imulator of IN terferon Genes) mediates protective cellular response to
microbial infection and tissue damage, but its aberrant activation can lead to …