The human intestine contains an intricate ecological community of dwelling bacteria,
referred as gut microbiota (GM), which plays a pivotal role in host homeostasis. Multiple …

Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of
tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in …

The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

The increased prevalence of type 2 diabetes mellitus (T2DM) and life expectancy of diabetic
patients fosters the worldwide prevalence of retinopathy and nephropathy, two major …

Scope We examined the intestinal and systemic responses to incorporating a type 2
resistant starch (RS) into a high fat diet fed to obese mice. Methods and results Diet‐induced …

The intestinal microflora maintains a symbiotic relationship with the host under normal
conditions, but its imbalance has recently been associated with several diseases. In chronic …

In healthy kidneys, interstitial fibroblasts are responsible for the maintenance of renal
architecture. Progressive interstitial fibrosis is thought to be a common pathway for chronic …

In chronic kidney disease (CKD), accumulation of uremic toxins is associated with an
increased risk of death. Some uremic toxins are ingested with the diet, such as phosphate …

Chronic kidney disease (CKD) is characterized by the accumulation of protein-bound uremic
toxins (PBUTs), which play a pathophysiological role in renal fibrosis (a common …

OBJECTIVE We investigated endotrophin, a profibrotic signaling molecule reflecting
collagen VI formation, in serum and urine as risk marker for complications to type 2 diabetes …