Mesenchymal stem/stromal cells in cancer therapy

T Lan, M Luo, X Wei - Journal of Hematology & Oncology, 2021 - Springer
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …

Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …

Therapeutic potential of mesenchymal stem cells for cancer therapy

A Hmadcha, A Martin-Montalvo, BR Gauthier… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Y Shi, L Du, L Lin, Y Wang - Nature reviews Drug discovery, 2017 - nature.com
Mesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), exist in many
tissues and are known to actively migrate to sites of tissue injury, where they participate in …

Mesenchymal stem cells: a new trend for cell therapy

X Wei, X Yang, Z Han, F Qu, L Shao… - Acta Pharmacologica …, 2013 - nature.com
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in
the clinic for approximately 10 years. From animal models to clinical trials, MSCs have …

Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise

TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …

Mesenchymal stem cell-based drug delivery strategy: from cells to biomimetic

HH Wu, Y Zhou, Y Tabata, JQ Gao - Journal of Controlled Release, 2019 - Elsevier
Owing to the diversity and ease of preparation of nanomaterials, the rational nanocarriers
with a rational design have become increasingly popular in medical researches. Although …

Bio-inspired, bioengineered and biomimetic drug delivery carriers

JW Yoo, DJ Irvine, DE Discher… - Nature reviews Drug …, 2011 - nature.com
Synthetic carriers such as polymer and lipid particles often struggle to meet clinical
expectations. Natural particulates—that range from pathogens to mammalian cells—are …

Recent progress of stem cell therapy in cancer treatment: molecular mechanisms and potential applications

DT Chu, TT Nguyen, NLB Tien, DK Tran, JH Jeong… - Cells, 2020 - mdpi.com
The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

Skin cancer and new treatment perspectives: A review

MCF Simoes, JJS Sousa, AACC Pais - Cancer letters, 2015 - Elsevier
Skin cancers are by far the most common malignancy of humans, particularly in the white
population. The growing incidence of cutaneous malignancies has heralded the need for …