The current epidemic of chronic obstructive pulmonary disease (COPD) has produced a
worldwide health care burden, approaching that imposed by transmittable infectious …

In contrast to other organs, the lung completes a significant portion of its development after
term birth. During this stage of alveolarization, division of the alveolar ducts into alveolar …

Hepatocellular carcinoma (HCC) develops on the background of chronic hepatitis.
Leukocytes found within the HCC microenvironment are implicated as regulators of tumour …

Rationale: There is increasing evidence for the presence of autoantibodies in chronic
obstructive pulmonary disease (COPD). Chronic oxidative stress is an essential component …

Cigarette smoke (CS) leads to increased oxidative stress, inflammation, and exaggerated
senescence, which are involved in the pathogenesis of chronic obstructive pulmonary …

The environmental, genetic, and/or age-related changes in proteostasis induce
inflammation, oxidative stress, and apoptosis. We quantified the correlation of protein …

Redox‐signaling is implicated in deleterious microglial activation underlying CNS disease,
but how ROS program aberrant microglial function is unknown. Here, the oxidation of NF‐κB …

Autophagy is a fundamental cellular process that eliminates long-lived proteins and
damaged organelles through lysosomal degradation pathway. Cigarette smoke (CS) …

Forkhead box class O 3a (FOXO3) is a member of the FoxO transcription factor subfamily,
which regulates the expression of target genes not only through DNA binding as a …

Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a
ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various …