Iron is both an essential nutrient for the growth of microorganisms, as well as a dangerous
metal due to its capacity to generate reactive oxygen species (ROS) via the Fenton reaction …

Siderophores are iron chelating molecules produced by nearly all organisms, most notably
by bacteria, to efficiently sequester the limited iron that is available in the environment …

Outer membrane vesicles (OMVs) can function as nanoscale vectors that mediate bacterial
interactions in microbial communities. How bacteria recognize and recruit OMVs inter …

DNA methylation is involved in a diversity of processes in bacteria, including maintenance of
genome integrity and regulation of gene expression. Here, using Caulobacter crescentus as …

Candida albicans is an opportunistic fungal pathogen that exists as normal flora in healthy
human bodies but causes life-threatening infections in immunocompromised patients. In …

The full regulatory potential of the ferric uptake regulator (Fur) family of proteins remains
undefined despite over 20 years of study. We report herein an integrated approach that …

Edwardsiella piscicida mediates hemorrhagic septicemia and is a leading pathogen of fish.
E. piscicida invades and colonizes macrophages using type III and VI secretion systems …

Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer
and for the fixation, sensing, and metabolism of gases. Others compete with those essential …

Selenoproteins serve important functions in many organisms, usually providing essential
oxidoreductase enzymatic activity, often for defense against toxic xenobiotic substances …

Background In the alpha subclass of proteobacteria iron homeostasis is controlled by
diverse iron responsive regulators. Caulobacter crescentus, an important freshwater α …