Mitochondria, which serve as the energy factories of cells, are involved in cell differentiation,
calcium homeostasis, amino acid and fatty acid metabolism and apoptosis. In response to …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

Background Hepatocellular carcinoma (HCC) is the world's third leading cause of cancer-
related death; due to the fast growth and high prevalence of tumor recurrence, the prognosis …

Mitochondria are essential organelles that play critical roles in energy metabolism,
apoptosis and various cellular processes. Accumulating evidence suggests that …

Pregnancy associated plasma protein-A (PAPP-A) plays an integral role in breast cancer
(BC), especially triple negative breast cancer (TNBC). This subtype accounts for the most …

Mitochondria are semiautonomous organelles with diverse metabolic and cellular functions
including anabolism and energy production through oxidative phosphorylation. Following …

Aging is the most robust risk factor for cancer development, with more than 60% of cancers
occurring in those aged 60 and above. However, how aging and tumorigenesis are …

The contributions of mitochondria to cancer have been recognized for decades. However,
the focus on the metabolic role of mitochondria and the diminutive size of the mitochondrial …

Hepatocellular carcinoma (HCC) is a common cause of cancer-associated death worldwide.
The mitochondrial unfolded protein response (UPRmt) not only maintains mitochondrial …

Simple Summary Mitochondria are important organelles in the human body, and they act as
a source of chemical energy for different cellular processes. Multiple copies of mitochondria …