[HTML][HTML] All roads lead to Rome: different molecular players converge to common toxic pathways in neurodegeneration
S Argueti-Ostrovsky, L Alfahel, J Kahn, A Israelson - Cells, 2021 - mdpi.com
Multiple neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD), Parkinson's
disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's disease (HD) are being …
disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's disease (HD) are being …
[HTML][HTML] The role of triggering receptor expressed on myeloid cells-1 (TREM-1) in central nervous system diseases
C Zhang, X Kan, B Zhang, H Ni, J Shao - Molecular Brain, 2022 - Springer
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a member of the
immunoglobulin superfamily and is mainly expressed on the surface of myeloid cells such …
immunoglobulin superfamily and is mainly expressed on the surface of myeloid cells such …
Early clues and molecular mechanism involved in neurodegenerative diseases induced in immature mice by combined exposure to polypropylene microplastics and …
G Yang, C Gong, X Zheng, F Hu, J Liu, T Wang… - Environmental …, 2023 - Elsevier
Studies have shown that exposure to either microplastics (MPs) or di-(2-ethylhexyl) phthalic
acid (DEHP) alone can cause neurotoxicity in animals, but it remains uncertain whether and …
acid (DEHP) alone can cause neurotoxicity in animals, but it remains uncertain whether and …
[HTML][HTML] Extracellular HSPs: the potential target for human disease therapy
DY Li, S Liang, JH Wen, JX Tang, SL Deng, YX Liu - Molecules, 2022 - mdpi.com
Heat shock proteins (HSPs) are highly conserved stress proteins known as molecular
chaperones, which are considered to be cytoplasmic proteins with functions restricted to the …
chaperones, which are considered to be cytoplasmic proteins with functions restricted to the …
[HTML][HTML] Protein interactome of amyloid-β as a therapeutic target
VF Lazarev, EA Dutysheva, IE Kanunikov, IV Guzhova… - Pharmaceuticals, 2023 - mdpi.com
The amyloid concept of Alzheimer's disease (AD) assumes the β-amyloid peptide (Aβ) as
the main pathogenic factor, which injures neural and other brain cells, causing their …
the main pathogenic factor, which injures neural and other brain cells, causing their …
[HTML][HTML] Closest horizons of Hsp70 engagement to manage neurodegeneration
AA Venediktov, OY Bushueva… - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Our review seeks to elucidate the current state-of-the-art in studies of 70-kilodalton-weighed
heat shock proteins (Hsp70) in neurodegenerative diseases (NDs). The family has already …
heat shock proteins (Hsp70) in neurodegenerative diseases (NDs). The family has already …
[HTML][HTML] Manipulation of HSP70-SOD1 expression modulates SH-SY5Y differentiation and susceptibility to oxidative stress-dependent cell damage: involvement in …
The differentiation of neural progenitors is a complex process that integrates different signals
to drive transcriptional changes, which mediate metabolic, electrophysiological, and …
to drive transcriptional changes, which mediate metabolic, electrophysiological, and …
[HTML][HTML] Heat shock proteins adaptive responses to environmental stressors and implications in health management of decapods
Heat shock proteins (HSPs) are highly conserved, cytoprotective proteins, the best know
function of which is to facilitate the proper folding of nascent proteins. Environmental …
function of which is to facilitate the proper folding of nascent proteins. Environmental …
[HTML][HTML] Damage to the Locus Coeruleus Alters the Expression of Key Proteins in Limbic Neurodegeneration
F Biagioni, M Ferrucci, G Lazzeri, M Scioli… - International Journal of …, 2024 - mdpi.com
The present investigation was designed based on the evidence that, in neurodegenerative
disorders, such as Alzheimer's dementia (AD) and Parkinson's disease (PD), damage to the …
disorders, such as Alzheimer's dementia (AD) and Parkinson's disease (PD), damage to the …
Identification and prioritization of PET neuroimaging targets for microglial phenotypes associated with microglial activity in Alzheimer's disease
ND Bartolo, N Mortimer, MA Manter… - ACS Chemical …, 2022 - ACS Publications
Activation of microglial cells accompanies the progression of many neurodegenerative
disorders, including Alzheimer's disease (AD). Development of molecular imaging tools …
disorders, including Alzheimer's disease (AD). Development of molecular imaging tools …