Although it is challenging for individuals with cocaine addiction to achieve abstinence, the
greatest difficulty is avoiding relapse to drug taking, which is often triggered by cues …

The last two decades have witnessed substantial advances in identifying synaptic plasticity
responsible for behavioral changes in animal models of substance use disorder. We have …

We recently introduced an animal model of incubation of methamphetamine craving after
choice-based voluntary abstinence in male rats. Here we studied the generality of this …

Sex differences in motivation for food rewards, gambling, and drugs of abuse are modulated
by multiple factors, including sensory stimuli, gonadal hormones, and cognitive bias. Cues …

Drug addiction is responsible for millions of deaths per year around the world. Still, its
management as a chronic disease is shadowed by misconceptions from the general public …

Cocaine use disorder and methamphetamine use disorder are chronic, relapsing disorders
with no US Food and Drug Administration-approved interventions. Repetitive transcranial …

Rates of individuals struggling with psychostimulant use disorder (PSUD), defined as
chronic use of psychostimulants despite negative consequences, are growing rapidly over …

Abstract In 1986, Gawin and Kleber reported a progressive increase in cue-induced drug
craving in individuals with cocaine use disorders during prolonged abstinence. After years of …

Astrocytes provide support for neurons, regulate metabolic processes, and influence
neuronal communication in a variety of ways, including through the homeostatic regulation …

Since the introduction of intravenous drug self-administration methodology over 50 years
ago, experimental investigation of addictive behaviour has delivered an enormous body of …