Revisiting netrin-1: one who guides (axons)
NP Boyer, SL Gupton - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Proper patterning of the nervous system requires that developing axons find appropriate
postsynaptic partners; this entails microns to meters of extension through an extracellular …
postsynaptic partners; this entails microns to meters of extension through an extracellular …
The growth cone cytoskeleton in axon outgrowth and guidance
Axon outgrowth and guidance to the proper target requires the coordination of filamentous
(F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape …
(F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape …
Oxidant signals and oxidative stress
T Finkel - Current opinion in cell biology, 2003 - Elsevier
Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …
fashion, growing evidence suggests that in many instances the production of reactive …
Regulation of neuronal development and function by ROS
MCW Oswald, N Garnham, ST Sweeney… - FEBS …, 2018 - Wiley Online Library
Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …
Semaphorins in adult nervous system plasticity and disease
D Carulli, F De Winter, J Verhaagen - Frontiers in synaptic …, 2021 - frontiersin.org
Semaphorins, originally discovered as guidance cues for developing axons, are involved in
many processes that shape the nervous system during development, from neuronal …
many processes that shape the nervous system during development, from neuronal …
[HTML][HTML] Oxidation and reduction of actin: Origin, impact in vitro and functional consequences in vivo
C Rouyère, T Serrano, S Frémont, A Echard - European journal of cell …, 2022 - Elsevier
Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …
The LIM domain: from the cytoskeleton to the nucleus
JL Kadrmas, MC Beckerle - Nature reviews Molecular cell biology, 2004 - nature.com
First described 15 years ago as a cysteine-rich sequence that was common to a small group
of homeodomain transcription factors, the LIM domain is now recognized as a tandem zinc …
of homeodomain transcription factors, the LIM domain is now recognized as a tandem zinc …
Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking
C Wilson, C González-Billault - Frontiers in cellular neuroscience, 2015 - frontiersin.org
A proper balance between chemical reduction and oxidation (known as redox balance) is
essential for normal cellular physiology. Deregulation in the production of oxidative species …
essential for normal cellular physiology. Deregulation in the production of oxidative species …
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome
In fruit fly research, chromosomal deletions are indispensable tools for mapping mutations,
characterizing alleles and identifying interacting loci. Most widely used deletions were …
characterizing alleles and identifying interacting loci. Most widely used deletions were …
Actin bundles dynamics and architecture
S Rajan, DS Kudryashov, E Reisler - Biomolecules, 2023 - mdpi.com
Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …