Virus-like particle vaccines and platforms for vaccine development
M Kheirvari, H Liu, E Tumban - Viruses, 2023 - mdpi.com
Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use
of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human …
of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human …
Phage display—A powerful technique for immunotherapy: 1. Introduction and potential of therapeutic applications
J Bazan, I Całkosiński, A Gamian - Human vaccines & …, 2012 - Taylor & Francis
One of the most effective molecular diversity techniques is phage display. This technology is
based on a direct linkage between phage phenotype and its encapsulated genotype, which …
based on a direct linkage between phage phenotype and its encapsulated genotype, which …
Virus-like particles for the prevention of human papillomavirus-associated malignancies
As compared with peptide-or protein-based vaccines, naked DNA vectors and even
traditional attenuated or inactivated virus vaccines, virus-like particles (VLPs) are an …
traditional attenuated or inactivated virus vaccines, virus-like particles (VLPs) are an …
A cholesterol-lowering VLP vaccine that targets PCSK9
E Crossey, MJA Amar, M Sampson, J Peabody… - Vaccine, 2015 - Elsevier
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secretory protein that controls
cholesterol homeostasis by enhancing endosomal and lysosomal degradation of the low …
cholesterol homeostasis by enhancing endosomal and lysosomal degradation of the low …
Nanoparticle-based adjuvants and delivery systems for modern vaccines
Ever since the development of the first vaccine, vaccination has had the great impact on
global health, leading to the decrease in the burden of numerous infectious diseases …
global health, leading to the decrease in the burden of numerous infectious diseases …
Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures
P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …
HPV vaccines to prevent cervical cancer and genital warts: an update
Cervical cancer is an important public health problem worldwide, and especially in
developing countries. The link between cervical cancer and oncogenic human …
developing countries. The link between cervical cancer and oncogenic human …
Dissolving microneedle delivery of a prophylactic HPV vaccine
S Ray, DM Wirth, OA Ortega-Rivera… - …, 2022 - ACS Publications
Prophylactic vaccines capable of preventing human papillomavirus (HPV) infections are still
inaccessible to a vast majority of the global population due to their high cost and challenges …
inaccessible to a vast majority of the global population due to their high cost and challenges …
Evidence that viral RNAs have evolved for efficient, two-stage packaging
A Borodavka, R Tuma… - Proceedings of the …, 2012 - National Acad Sciences
Genome packaging is an essential step in virus replication and a potential drug target.
Single-stranded RNA viruses have been thought to encapsidate their genomes by gradual …
Single-stranded RNA viruses have been thought to encapsidate their genomes by gradual …
RG1-VLP and other L2-based, broad-spectrum HPV vaccine candidates
B Huber, JW Wang, RBS Roden… - Journal of Clinical …, 2021 - mdpi.com
Licensed human papillomavirus (HPV) vaccines contain virus-like particles (VLPs) self-
assembled from L1 major-capsid proteins that are remarkably effective prophylactic …
assembled from L1 major-capsid proteins that are remarkably effective prophylactic …