[HTML][HTML] Symphytum Species: A Comprehensive Review on Chemical Composition, Food Applications and Phytopharmacology

B Salehi, F Sharopov, T Boyunegmez Tumer… - Molecules, 2019 - mdpi.com
Symphytum species belongs to the Boraginaceae family and have been used for centuries
for bone breakages, sprains and rheumatism, liver problems, gastritis, ulcers, skin problems …

[HTML][HTML] Evidence for natural products as alternative wound-healing therapies

RL Moses, TAK Prescott, E Mas-Claret, R Steadman… - Biomolecules, 2023 - mdpi.com
Chronic, non-healing wounds represent a significant area of unmet medical need and are a
growing problem for healthcare systems around the world. They affect the quality of life for …

[HTML][HTML] Small molecules of herbal origin for osteoarthritis treatment: in vitro and in vivo evidence

P Zhang, K Li, A Kamali, R Ziadlou, P Ahmad… - Arthritis research & …, 2022 - Springer
Osteoarthritis (OA) is one of the most common musculoskeletal degenerative diseases and
contributes to heavy socioeconomic burden. Current pharmacological and conventional non …

Proliferative and antioxidant activity of Symphytum officinale root extract

I Sowa, R Paduch, M Strzemski, S Zielińska… - Natural product …, 2018 - Taylor & Francis
The root of Symphytum officinale L. is commonly used in folk medicine to promote the wound
healing, reduce the inflammation and in the treatment of broken bones. The objective of our …

[HTML][HTML] A Symphytum officinale Root Extract Exerts Anti-inflammatory Properties by Affecting Two Distinct Steps of NF-κB Signaling

J Seigner, M Junker-Samek, A Plaza… - Frontiers in …, 2019 - frontiersin.org
Symphytum officinale, commonly known as comfrey, constitutes a traditional medicinal plant
with a long-standing therapeutic history, and preparations thereof have been widely used for …

[HTML][HTML] Antimicrobial Antioxidant Polymer Films with Green Silver Nanoparticles from Symphyti radix

A Balciunaitiene, V Januskevice, S Saunoriute… - Polymers, 2024 - mdpi.com
Antimicrobial natural polymer film with silver nanoparticles (AgNPs) biosynthesized using
aqueous plant root extracts as reducing capping agents and for film formatting show …

[HTML][HTML] A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey …

C Avila, I Breakspear, J Hawrelak, S Salmond, S Evans - Fitoterapia, 2020 - Elsevier
Symphytum officinale (comfrey), Tussilago farfara (coltsfoot) and Borago officinalis (borage)
have long histories of therapeutic use, but their safety has been questioned due to the …

[HTML][HTML] Phytochemical Analysis of Symphytum officinale Root Culture Extract

V Le, V Dolganyuk, A Sukhikh, O Babich, S Ivanova… - Applied Sciences, 2021 - mdpi.com
Comfrey (Symphytum officinale) root preparations are known for their analgesic and anti-
inflammatory properties. In this study, the phenolic profile of extract samples of Symphytum …

[HTML][HTML] Remnants from the Past: From an 18th Century Manuscript to 21st Century Ethnobotany in Valle Imagna (Bergamo, Italy)

F Milani, M Bottoni, L Bardelli, L Colombo, PS Colombo… - Plants, 2023 - mdpi.com
Background: This project originated from the study of an 18th century manuscript found in
Valle Imagna (Bergamo, Italy) which contains 200 plant-based medicinal remedies. A first …

A design-of-experiment approach for obtaining Symphytum officinale L. extracts for cosmetic purposes

S Dresler, A Ziemlewska, Z Nizioł-Łukaszewska… - Industrial Crops and …, 2023 - Elsevier
Promotion of wound or bone healing and reduction of inflammation are commonly known
therapeutic qualities of comfrey (Symphytum officinale). Given the presence of active …