As part of their life cycle, neutralophilic bacteria are often exposed to varying environmental
stresses, among which fluctuations in pH are the most frequent. In particular, acid …

Escherichia coli has a remarkable ability to survive low pH and possesses a number of
different genetic systems that enable it to do this. These may be expressed constitutively …

In bacteria, Hfq is a core RNA chaperone that catalyzes the interaction of mRNAs with
regulatory small RNAs (sRNAs). To determine in vivo RNA sequence requirements for Hfq …

Polylysogeny is frequently considered to be the result of an adaptive evolutionary process in
which prophages confer fitness and/or virulence factors, thus making them important for …

Abstract The regulators GadE, GadW and GadX (which we refer to as GadEWX) play a
critical role in the transcriptional regulation of the glutamate-dependent acid resistance …

Enterohaemorrhagic Escherichia coli (EHEC) binds to host tissue and intimately attaches to
intestinal cells using a dedicated type III secretion system (T3SS). This complex multi-protein …

Attaching and effacing (AE) pathogens colonize the gut mucosa using a type three secretion
system (T3SS) and a suite of effector proteins. The locus of enterocyte effacement (LEE) is …

Escherichia coli comprise a diverse array of both commensals and niche-specific
pathotypes. The ability to cause disease results from both carriage of specific virulence …

The ability of any organism to sense and respond to challenges presented in the
environment is critically important for promoting or restricting colonization of specific sites …

Expression of genes of the locus of enterocyte effacement (LEE) is essential for adherence
of enterohemorrhagic Escherichia coli (EHEC) to intestinal epithelial cells. Gut factors that …