Thiazolidinones: Synthesis, reactivity, and their biological applications
Thiazolidinone is a biologically important five‐membered heterocyclic ring having almost all
types of biological activities. This review covers various types of thiazolidinones, such as 2 …
types of biological activities. This review covers various types of thiazolidinones, such as 2 …
Review on synthetic chemistry and antibacterial importance of thiazole derivatives
A Kashyap, N Adhikari, A Das, A Shakya… - Current drug …, 2018 - ingentaconnect.com
Background: Thiazole is one of the leading heterocyclic five-member ring compounds that
contain nitrogen and sulphur atom. Many natural and/or synthetic compounds contain …
contain nitrogen and sulphur atom. Many natural and/or synthetic compounds contain …
In vitro antioxidant activity of thiazolidinone derivatives of 1, 3-thiazole and 1, 3, 4-thiadiazole
M Djukic, M Fesatidou, I Xenikakis, A Geronikaki… - Chemico-Biological …, 2018 - Elsevier
The initial steps in preclinical drug developing research concern the synthesis of new
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …
compounds for specific therapeutic use which needs to be confirmed by in vitro and then in …
[HTML][HTML] Development of novel isatin thiazolyl-pyrazoline hybrids as promising antimicrobials in MDR pathogens
Microbial Multidrug Resistance (MDR) is an emerging global crisis. Derivatization of natural
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …
or synthetic scaffolds is among the most reliable strategies to search for and obtain novel …
[HTML][HTML] Synthesis of novel benzimidazole-based thiazole derivatives as multipotent inhibitors of α-amylase and α-glucosidase: in vitro evaluation along with molecular …
In this study, hybrid analogs of benzimidazole containing a thiazole moiety (1–17) were
afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when …
afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when …
[HTML][HTML] Imidazopyridine-based thiazole derivatives as potential antidiabetic agents: synthesis, in vitro bioactivity, and in silico molecular modeling approach
A new series of thiazole derivatives (4a-p) incorporating imidazopyridine moiety was
synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose …
synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose …
5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation
M Fesatidou, P Zagaliotis, C Camoutsis… - Bioorganic & Medicinal …, 2018 - Elsevier
In continuation of our efforts to develop new compounds with antimicrobial properties we
describe design, synthesis, molecular docking study and evaluation of antimicrobial activity …
describe design, synthesis, molecular docking study and evaluation of antimicrobial activity …
Unravelling the thermodynamics and binding interactions of bovine serum albumin (BSA) with thiazole based carbohydrazide: Multi-spectroscopic, DFT and molecular …
In the present manuscript, a novel 2-((4-chlorophenyl) amino)-N'-(4-(diethylamino)-2-
hydroxybenzylidene) thiazole-4-carbohydrazide (H1) has been synthesized and …
hydroxybenzylidene) thiazole-4-carbohydrazide (H1) has been synthesized and …
New thiazole and thiazole-chromene hybrids possessing morpholine units: Piperazine-mediated one-pot synthesis of potential acetylcholinesterase inhibitors
In the current study, new morpholine-linked thiazoles were prepared by the reaction of
salicylaldehyde derivative, thiosemicarbazide, and α-bromoketones. To mediate the …
salicylaldehyde derivative, thiosemicarbazide, and α-bromoketones. To mediate the …
New benzothiazole-based thiazolidinones as potent antimicrobial agents. Design, synthesis and biological evaluation
Background: Thiazole and benzothiazole derivatives, as well as thiazolidinones are very
important scaffolds in medicinal chemistry. Literature has revealed that they possess a wide …
important scaffolds in medicinal chemistry. Literature has revealed that they possess a wide …