Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …

RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …

Chronic kidney disease (CKD) has been recognized as a leading public health problem
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …

There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …

Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Increasing evidence has suggested that paracrine mechanisms might be involved in the
underlying mechanism of mesenchymal stem cells (MSCs) transplantation, and exosomes …

Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid
bilayers without organelles. In recent years, an increasing number of researchers have …

The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …