Simple Summary Immature T-cell acute lymphoblastic leukemias englobes a wide range of
low prevalence subtypes, not well identified, that in some cases overlap with myeloid …

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy
with a dismal prognosis related to refractory/relapsing diseases, raising the need for new …

Constitutively active casein kinase 2 (CK2) signaling is a common feature of T-cell acute
lymphoblastic leukemia (T-ALL). CK2 phosphorylates PTEN (phosphatase and tensin …

Constitutively active phosphoinositide 3-kinase (PI3K) signaling is a common feature of T-
cell acute lymphoblastic leukemia (T-ALL), where it upregulates cell proliferation, survival …

T-cell acute lymphoblastic leukemia (T-ALL) is a heterogeneous neoplastic disorder of
immature hematopoietic precursors committed to the T-cell lineage. T-ALL comprises about …

T-cell acute lymphoblastic leukemia (T-ALL) represents the malignant expansion of
immature T cells blocked in their differentiation. T-ALL is still associated with a poor …

Simple Summary The prevalence of FLT3-ITD among children with ETP-ALL must be
determined. MRD monitoring in ETPs is hampered by the lack of Immunoglobulin (IG) and T …

T-cell acute lymphoblastic leukemia (T-ALL) represents expansion of cells arrested at
specific stages of thymic development with the underlying genetic abnormality often …

Lmo2 is an oncogenic transcription factor that is frequently overexpressed in T-cell acute
leukemias, in particular poor prognosis early T-cell precursor-like (ETP-) acute …

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, and T-cell
ALL (T-ALL) accounts for approximately 15% of cases of childhood ALL. 1, 2 Early T-cell …