Purpose.: To characterize a glaucoma model of mice, the authors adopted and modified a
method of inducing the chronic elevation of intraocular pressure (IOP) by anterior chamber …

Purpose.: To characterize expression of the RNA binding protein (RBPMS) in the retina as a
specific marker for retinal ganglion cells (RGCs). Methods.: Optic nerve transection (ONT) …

Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during
development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs …

Purpose: Adult central nervous system (CNS) neurons are unable to regenerate their axons
after injury. Krüppel-like transcription factor (KLF) family members regulate intrinsic axon …

Our group has shown that the polysaccharides extracted from Lycium barbarum (LBP) are
neuroprotective for retinal ganglion cells (RGCs) in different animal models. Protecting …

Wolfberry (fruit of Lycium barbarum Linn) has been known for balancing 'Yin'and 'Yang'in the
body, nourishing the liver and kidney, improving visual acuity for more than 2,500 years in …

Background Glaucoma is one of the leading causes of irreversible blindness in the world.
The major risk factor is elevated intraocular pressure (IOP) leading to progressive retinal …

AIM To evaluate the reliability of β-III-Tubulin protein as a retinal ganglion cell (RGC) marker
in the experimental glaucoma model. METHODS Glaucoma mouse models were …

The active component of Wolfberry (Lycium barbarum), lycium barbarum polysaccharides
(LBP), has been shown to be neuroprotective to retinal ganglion cells (RGCs) against ocular …

Abstract Epigallocatechin-3-gallate (EGCG) is a powerful antioxidant with suggested
neuroprotective action. This study investigated the protective effects of EGCG against retinal …