Nanosecond Pulsed Electric Field (nsPEF) is an electrostimulation technique first developed
in 1995; nsPEF requires the delivery of a series of pulses of high electric fields in the order of …

Conventional electric stimuli of micro-and millisecond duration excite or activate cells at
voltages 10–100 times below the electroporation threshold. This ratio is remarkably different …

Common delivery routes for chemotherapeutics are based on circulation, which faces
clinical limitations to local delivery efficiency, and the conflict between the dose for …

Introduction Pulsed field ablation (PFA) exploits the delivery of short high-voltage shocks to
induce cells death via irreversible electroporation. The therapy offers a potential paradigm …

Intense nanosecond pulsed electric field (nsPEF) is a novel modality for cell activation and
nanoelectroporation. Applications of nsPEF in research and therapy are hindered by a high …

Stimulation and electroporation by nanosecond electric pulses (nsEP) are distinguished by
a phenomenon of bipolar cancellation, which stands for a reduced efficiency of bipolar …

Targeted cellular ablation is being increasingly used in the treatment of arrhythmias and
structural heart disease. Catheter-based ablation for atrial fibrillation (AF) is considered a …

Electroporation is a biophysical phenomenon involving an increase in cell membrane
permeability to molecules after a high-pulsed electric field is applied to the tissue. Currently …

We compared membrane permeabilization by nanosecond pulsed electric field (nsPEF) in
HEK293 cells with and without assembled CaV1. 3 L-type voltage-gated calcium channel …

Background: Irreversible electroporation is an energy form utilizing high-voltage pulsed
electric field, leading to cellular homeostasis disruption and cell death. Recently, irreversible …