Histones serve to both package and organize DNA within the nucleus. In addition to histone
post-translational modification and chromatin remodelling complexes, histone variants …

The packaging of DNA into strings of nucleosomes is one of the features that allows
eukaryotic cells to tightly regulate gene expression. The ordered disassembly of …

Histone variants endow chromatin with unique properties and show a specific genomic
distribution that is regulated by specific deposition and removal machineries. These variants …

The function of sperm is to safely transport the haploid paternal genome to the egg
containing the maternal genome. The subsequent fertilization leads to transmission of a new …

Despite a conserved role for histones as general DNA packaging agents, it is now clear that
another key function of these proteins is to confer variations in chromatin structure to ensure …

The past decade has seen a tremendous increase in interest and progress in the field of
sperm epigenetics. Studies have shown that chromatin regulation during male germline …

Histone variants are non-allelic protein isoforms that play key roles in diversifying chromatin
structure. The known number of such variants has greatly increased in recent years, but the …

Information encoded in DNA is interpreted, modified, and propagated as chromatin. The
diversity of inputs encountered by eukaryotic genomes demands a matching capacity for …

In this review, we describe the attributes of histone H3 mutants identified in cancer. H3
mutants were first identified in genes encoding H3. 3, in pediatric high-grade glioma, and …

Histones have a long history of research in a wide range of species, leaving a legacy of
complex nomenclature in the literature. Community-led discussions at the EMBO Workshop …