Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle

M Forutan, S Ansari Mahyari, C Baes, N Melzer… - BMC genomics, 2018 - Springer
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …

Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle

E Peripolli, NB Stafuzza, DP Munari, ALF Lima… - BMC genomics, 2018 - Springer
Background Runs of homozygosity (ROH) are continuous homozygous segments of the
DNA sequence. They have been applied to quantify individual autozygosity and used as a …

[HTML][HTML] Current applications and perspectives of genomic selection in Bos indicus (Nellore) cattle

GAF Júnior, E Peripolli, PI Schmidt, GS Campos… - Livestock Science, 2022 - Elsevier
Bos indicus cattle acquired very particular traits to thrive in distinct environments based on
the evolutionary adaptation process they have undergone, becoming particularly relevant for …

[HTML][HTML] Runs of homozygosity for autozygosity estimation and genomic analysis in production animals

AB Rebelato, AR Caetano - Pesquisa Agropecuária Brasileira, 2018 - SciELO Brasil
Runs of homozygosity (ROHs) are long stretches of homozygous genomic segments,
identifiable by molecular markers, which can provide genomic information for accurate …

[HTML][HTML] The pattern of runs of homozygosity and genomic inbreeding in world-wide sheep populations

M Nosrati, HA Nanaei, A Javanmard, A Esmailizadeh - Genomics, 2021 - Elsevier
Genome-wide pattern of runs of homozygosity (ROH) across ovine genome can provide a
useful resource for studying diversity and demography history in sheep. We analyzed 50 k …

Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits

E Peripolli, J Metzger, MVA De Lemos, NB Stafuzza… - BMC genomics, 2018 - Springer
Background The aim of this study was to assess genome-wide autozygosity in a Nellore
cattle population and to characterize ROH patterns and autozygosity islands that may have …

A PLAG1 mutation contributed to stature recovery in modern cattle

YT Utsunomiya, M Milanesi, ATH Utsunomiya… - Scientific reports, 2017 - nature.com
The recent evolution of cattle is marked by fluctuations in body size. Height in the Bos taurus
lineage was reduced by a factor of~ 1.5 from the Neolithic to the Middle Ages, and increased …

Identification of candidate lethal haplotypes and genomic association with post-natal mortality and reproductive traits in Nellore cattle

PI Schmidt, LFM Mota, LFS Fonseca… - Scientific Reports, 2023 - nature.com
The wide use of genomic information has enabled the identification of lethal recessive
alleles that are the major genetic causes of reduced conception rates, longer calving …

Estimates of autozygosity through runs of homozygosity in farmed coho salmon

GM Yoshida, P Cáceres, R Marín-Nahuelpi, BF Koop… - Genes, 2020 - mdpi.com
The characterization of runs of homozygosity (ROH), using high-density single nucleotide
polymorphisms (SNPs) allows inferences to be made about the past demographic history of …

Identification of genetic regions associated with scrotal hernias in a commercial swine herd

LV Lago, A Nery da Silva, EL Zanella… - Veterinary …, 2018 - mdpi.com
In this paper, we have used two approaches to detect genetic associations with scrotal
hernias in commercial pigs. Firstly, we have investigated the effects of runs of homozygosity …