Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …
limited information on the ability of different methods to measure true inbreeding. In the …
Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle
E Peripolli, NB Stafuzza, DP Munari, ALF Lima… - BMC genomics, 2018 - Springer
Background Runs of homozygosity (ROH) are continuous homozygous segments of the
DNA sequence. They have been applied to quantify individual autozygosity and used as a …
DNA sequence. They have been applied to quantify individual autozygosity and used as a …
[HTML][HTML] Current applications and perspectives of genomic selection in Bos indicus (Nellore) cattle
GAF Júnior, E Peripolli, PI Schmidt, GS Campos… - Livestock Science, 2022 - Elsevier
Bos indicus cattle acquired very particular traits to thrive in distinct environments based on
the evolutionary adaptation process they have undergone, becoming particularly relevant for …
the evolutionary adaptation process they have undergone, becoming particularly relevant for …
[HTML][HTML] Runs of homozygosity for autozygosity estimation and genomic analysis in production animals
AB Rebelato, AR Caetano - Pesquisa Agropecuária Brasileira, 2018 - SciELO Brasil
Runs of homozygosity (ROHs) are long stretches of homozygous genomic segments,
identifiable by molecular markers, which can provide genomic information for accurate …
identifiable by molecular markers, which can provide genomic information for accurate …
[HTML][HTML] The pattern of runs of homozygosity and genomic inbreeding in world-wide sheep populations
Genome-wide pattern of runs of homozygosity (ROH) across ovine genome can provide a
useful resource for studying diversity and demography history in sheep. We analyzed 50 k …
useful resource for studying diversity and demography history in sheep. We analyzed 50 k …
Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits
E Peripolli, J Metzger, MVA De Lemos, NB Stafuzza… - BMC genomics, 2018 - Springer
Background The aim of this study was to assess genome-wide autozygosity in a Nellore
cattle population and to characterize ROH patterns and autozygosity islands that may have …
cattle population and to characterize ROH patterns and autozygosity islands that may have …
A PLAG1 mutation contributed to stature recovery in modern cattle
The recent evolution of cattle is marked by fluctuations in body size. Height in the Bos taurus
lineage was reduced by a factor of~ 1.5 from the Neolithic to the Middle Ages, and increased …
lineage was reduced by a factor of~ 1.5 from the Neolithic to the Middle Ages, and increased …
Identification of candidate lethal haplotypes and genomic association with post-natal mortality and reproductive traits in Nellore cattle
PI Schmidt, LFM Mota, LFS Fonseca… - Scientific Reports, 2023 - nature.com
The wide use of genomic information has enabled the identification of lethal recessive
alleles that are the major genetic causes of reduced conception rates, longer calving …
alleles that are the major genetic causes of reduced conception rates, longer calving …
Estimates of autozygosity through runs of homozygosity in farmed coho salmon
The characterization of runs of homozygosity (ROH), using high-density single nucleotide
polymorphisms (SNPs) allows inferences to be made about the past demographic history of …
polymorphisms (SNPs) allows inferences to be made about the past demographic history of …
Identification of genetic regions associated with scrotal hernias in a commercial swine herd
LV Lago, A Nery da Silva, EL Zanella… - Veterinary …, 2018 - mdpi.com
In this paper, we have used two approaches to detect genetic associations with scrotal
hernias in commercial pigs. Firstly, we have investigated the effects of runs of homozygosity …
hernias in commercial pigs. Firstly, we have investigated the effects of runs of homozygosity …