Condensation-Based Methods for the C–H Bond Functionalization of Amines
W Chen, D Seidel - Synthesis, 2021 - thieme-connect.com
This review aims to provide a comprehensive overview of condensation-based methods for
the C–H bond functionalization of amines that feature azomethine ylides as key …
the C–H bond functionalization of amines that feature azomethine ylides as key …
Redox-neutral functionalization of α-Csp 3–H bonds of secondary cyclic amines: a highly atom-economical strategy for N-arylation/formal cross-dehydrogenative …
An efficient redox-neutral method has been developed for α-Csp3–H functionalization of
secondary cyclic amines via concurrent N-arylation/formal cross dehydrogenation coupling …
secondary cyclic amines via concurrent N-arylation/formal cross dehydrogenation coupling …
Metal-Free Sequential C(sp2)–H/OH and C(sp3)–H Aminations of Nitrosoarenes and N-Heterocycles to Ring-Fused Imidazoles
Hydrogen bond assisted ortho-selective C (sp2)–H amination of nitrosoarenes and
subsequent α-C (sp3)-H functionalization of aliphatic amines is achieved under metal-free …
subsequent α-C (sp3)-H functionalization of aliphatic amines is achieved under metal-free …
Redox‐Neutral Aromatization of Cyclic Amines: Mechanistic Insights and Harnessing of Reactive Intermediates for Amine α‐and β‐C− H Functionalization
Cyclic amines such as pyrrolidine and piperidine are known to undergo condensations with
aldehydes to furnish pyrrole and pyridine derivatives, respectively. A combined experimental …
aldehydes to furnish pyrrole and pyridine derivatives, respectively. A combined experimental …
Redox-annulation of cyclic amines and β-ketoaldehydes
W Chen, D Seidel - Organic letters, 2016 - ACS Publications
Benzo [a] quinolizine-2-one derivatives are readily assembled from 1, 2, 3, 4-
tetrahydroisoquinoline and β-ketoaldehydes by means of a new intramolecular redox …
tetrahydroisoquinoline and β-ketoaldehydes by means of a new intramolecular redox …
Classical‐Reaction‐Driven Stereo‐ and Regioselective C(sp3)–H Functionalization of Aliphatic Amines
S Mahato, CK Jana - The Chemical Record, 2016 - Wiley Online Library
A large variety of synthetic methods have been developed for the synthesis of functionalized
aliphatic amines because of their broad spectrum of application. Metallic reagents/catalysts …
aliphatic amines because of their broad spectrum of application. Metallic reagents/catalysts …
Acetic acid promoted redox annulations with dual C–H functionalization
Z Zhu, D Seidel - Organic letters, 2017 - ACS Publications
Amines such as 1, 2, 3, 4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-
alkylquinoline-3-carbaldehydes as well as the corresponding 4-alkyl isomers and pyridine …
alkylquinoline-3-carbaldehydes as well as the corresponding 4-alkyl isomers and pyridine …
Redox-neutral α-C–H functionalization of pyrrolidin-3-ol
CB Yi, ZY She, YF Cheng, J Qu - Organic letters, 2018 - ACS Publications
A redox-neutral α-C–H oxygenation of commercially available pyrrolidin-3-ol with a
monoprotected p-quinone generated an N-aryliminium ion intermediate, which reacted in …
monoprotected p-quinone generated an N-aryliminium ion intermediate, which reacted in …
Metal free C–H functionalization enabled diastereoselective multicomponent reaction of N-heterocycles to fused heteropolycycles
A novel C–H functionalization enabled multicomponent reaction involving N-heterocycles,
dinucleophile, and dipolarophile has been developed. Direct α-and more challenging β-C …
dinucleophile, and dipolarophile has been developed. Direct α-and more challenging β-C …
An Ugi reaction incorporating a redox-neutral amine C–H functionalization step
Z Zhu, D Seidel - Organic letters, 2016 - ACS Publications
An Ugi Reaction Incorporating a Redox-Neutral Amine C–H Functionalization Step | Organic
Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS …
Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS …