In an increasing number of states and countries, cannabis now stands poised to join alcohol
and tobacco as a legal drug. Quantifying the relative adverse and beneficial effects of …

Purpose The NESARC, a “third-generation” psychiatric epidemiologic survey that integrated
detailed measures of alcohol and drug use and problems has been the data source for …

Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

With the increasing push to legalize cannabis in Western nations, there is a need to gage
the potential impact of this policy change on vulnerable populations, such as those with …

Aims To examine changes in the evidence on the adverse health effects of cannabis since
1993. Methods A comparison of the evidence in 1993 with the evidence and interpretation of …

Background 'Optimal outcomes' of child and adolescent psychiatric disorders may mean the
best possible outcome, or the best considering a child's history. Most research into the …

Background Frequent cannabis users are at high risk of dependence, still most (near) daily
users are not dependent. It is unknown why some frequent users develop dependence …

Continued increases in overdose deaths and recent declines in life expectancy call for need
to adopt comprehensive public health approaches to the United States opioid crisis and to …

This review summarizes evidence on the effects of cannabis use on the development of
adolescents and young adults. It draws on epidemiological studies, neuroimaging studies …

Childhood trauma and post-childhood chronic/repeated stress could increase the risk of a
substance use disorder by affecting five stages of addiction illness-course:(a) initial …