Vitiligo: a review

C Bergqvist, K Ezzedine - Dermatology, 2020 - karger.com
Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of
the population worldwide. The disease is characterized by the selective loss of melanocytes …

Vitiligo treatments: review of current therapeutic modalities and JAK inhibitors

KN Cunningham, D Rosmarin - American journal of clinical dermatology, 2023 - Springer
Vitiligo is a chronic autoimmune disease characterized by loss of pigment of the skin,
affecting 0.5–2% of the population worldwide. It can have a significant impact on patients' …

CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo

M Rashighi, P Agarwal, JM Richmond… - Science translational …, 2014 - science.org
Vitiligo is an autoimmune disease of the skin that results in disfiguring white spots. There are
no US Food and Drug Administration–approved treatments for vitiligo, and most off-label …

Afamelanotide and narrowband UV-B phototherapy for the treatment of vitiligo: a randomized multicenter trial

HW Lim, PE Grimes, O Agbai, I Hamzavi… - JAMA …, 2015 - jamanetwork.com
Importance Narrowband UV-B (NB–UV-B) phototherapy is used extensively to treat vitiligo.
Afamelanotide, an analogue of α–melanocyte-stimulating hormone, is known to induce …

Treatment outcomes of topical calcineurin inhibitor therapy for patients with vitiligo: a systematic review and meta-analysis

JH Lee, HS Kwon, HM Jung, H Lee, GM Kim… - JAMA …, 2019 - jamanetwork.com
Importance Topical calcineurin inhibitors (TCIs), including tacrolimus and pimecrolimus,
have been widely used for the treatment of vitiligo; however, the efficacy of TCI monotherapy …

A practical approach to the diagnosis and treatment of vitiligo in children

K Ezzedine, N Silverberg - Pediatrics, 2016 - publications.aap.org
Vitiligo is a chronic, acquired depigmenting condition of the skin, and sometimes of the
mucosa, that results in the selective loss of melanocytes. 1 Vitiligo has been reported since …

Phototherapy and combination therapies for vitiligo

S Esmat, RA Hegazy, S Shalaby, SCS Hu… - Dermatologic …, 2017 - derm.theclinics.com
Vitiligo is a disease characterized by disappearance of melanocytes from the skin. It can
negatively influence the physical appearance of affected individuals, and may profoundly …

Concise review of recent studies in vitiligo

M Allam, H Riad - Qatar medical journal, 2014 - qscience.com
Vitiligo is an acquired pigmentry disorder of the skin and mucous membranes which
manifests as white macules and patches due to selective loss of melanocytes. Etiological …

Interventions for vitiligo

K Ezzedine, M Whitton, M Pinart - Jama, 2016 - jamanetwork.com
Clinical Question Which interventions are associated with highest efficacy and fewest
adverse events for treating vitiligo? Bottom Line Combination therapies, particularly those …

IFN‑γ induces apoptosis in human melanocytes by activating the JAK1/STAT1 signaling pathway

Q Su, F Wang, Z Dong, M Chen… - Molecular medicine …, 2020 - spandidos-publications.com
The present study aimed to investigate the role of janus kinase (JAK) 1/STAT1 in interferon
(IFN)‑γ‑induced apoptosis in human melanocytes. Following IFN‑γ treatment, the viability of …