Viewpoints: how the hippocampus contributes to memory, navigation and cognition

J Lisman, G Buzsáki, H Eichenbaum, L Nadel… - Nature …, 2017 - nature.com
Viewpoints: how the hippocampus contributes to memory, navigation and cognition | Nature
Neuroscience Skip to main content Thank you for visiting nature.com. You are using a browser …

[HTML][HTML] Immediate early genes, memory and psychiatric disorders: focus on c-Fos, Egr1 and Arc

FT Gallo, C Katche, JF Morici, JH Medina… - Frontiers in behavioral …, 2018 - frontiersin.org
Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …

[HTML][HTML] Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish

L Smirnova, BS Caffo, DH Gracias, Q Huang… - Frontiers in …, 2023 - frontiersin.org
Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …

[PDF][PDF] The Tolman-Eichenbaum machine: unifying space and relational memory through generalization in the hippocampal formation

JCR Whittington, TH Muller, S Mark, G Chen, C Barry… - Cell, 2020 - cell.com
The hippocampal-entorhinal system is important for spatial and relational memory tasks. We
formally link these domains, provide a mechanistic understanding of the hippocampal role in …

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

M Piwecka, P Glažar, LR Hernandez-Miranda… - Science, 2017 - science.org
INTRODUCTION Recently, a special class of RNAs has excited researchers and triggered
hundreds of now-published studies. Known as circular RNAs (circRNAs), these RNAs are …

[PDF][PDF] The neuronal gene arc encodes a repurposed retrotransposon gag protein that mediates intercellular RNA transfer

ED Pastuzyn, CE Day, RB Kearns, M Kyrke-Smith… - Cell, 2018 - cell.com
The neuronal gene Arc is essential for long-lasting information storage in the mammalian
brain, mediates various forms of synaptic plasticity, and has been implicated in …

[HTML][HTML] Fos ensembles encode and shape stable spatial maps in the hippocampus

NL Pettit, EL Yap, ME Greenberg, CD Harvey - Nature, 2022 - nature.com
In the hippocampus, spatial maps are formed by place cells while contextual memories are
thought to be encoded as engrams,,,,–. Engrams are typically identified by expression of the …

A shared neural ensemble links distinct contextual memories encoded close in time

DJ Cai, D Aharoni, T Shuman, J Shobe, J Biane… - Nature, 2016 - nature.com
Recent studies suggest that a shared neural ensemble may link distinct memories encoded
close in time,,,,,,,,,,,. According to the memory allocation hypothesis,, learning triggers a …

Near-atomic model of microtubule-tau interactions

EH Kellogg, NMA Hejab, S Poepsel, KH Downing… - Science, 2018 - science.org
Tau is a developmentally regulated axonal protein that stabilizes and bundles microtubules
(MTs). Its hyperphosphorylation is thought to cause detachment from MTs and subsequent …

Finding the engram

SA Josselyn, S Köhler, PW Frankland - Nature Reviews Neuroscience, 2015 - nature.com
Many attempts have been made to localize the physical trace of a memory, or engram, in the
brain. However, until recently, engrams have remained largely elusive. In this Review, we …