Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders

A Bhat, B Ray, AM Mahalakshmi, S Tuladhar… - Pharmacological …, 2020 - Elsevier
Phosphodiesterases (PDE) are a diverse family of enzymes (11 isoforms so far identified)
responsible for the degradation of cyclic adenosine monophosphate (cAMP) and cyclic …

Current and emerging pharmacological targets and treatments of urinary incontinence and related disorders

MC Michel, L Cardozo, CJ Chermansky, F Cruz… - Pharmacological …, 2023 - ASPET
Overactive bladder syndrome with and without urinary incontinence and related conditions,
signs, and disorders such as detrusor overactivity, neurogenic lower urinary tract …

Advances in In2O3-based materials for the development of hydrogen sulfide sensors

V Kumar, SM Majhi, KH Kim, HW Kim… - Chemical Engineering …, 2021 - Elsevier
The presence of H 2 S is an incisive indicator to assess the quality of indoor and/or outdoor
air. A number of metal oxide sensors have been developed to measure the concentration …

[HTML][HTML] The Impact of Drugs on Hydrogen Sulfide Homeostasis in Mammals

A Alsaeedi, S Welham, P Rose, YZ Zhu - Antioxidants, 2023 - mdpi.com
Mammalian cells and tissues have the capacity to generate hydrogen sulfide gas (H2S) via
catabolic routes involving cysteine metabolism. H2S acts on cell signaling cascades that are …

[HTML][HTML] In vitro inhibition of phosphodiesterase type 4 enhances rat corpus cavernosum nerve-mediated relaxation induced by gasotransmitters

VS Fernandes, ME López-Oliva, MP Martínez… - Life Sciences, 2022 - Elsevier
Aims Nitric oxide (NO) and hydrogen sulfide (H 2 S) are involved in nerve-mediated corpus
cavernosum (CC) relaxation. Expression of phosphodiesterase type 5 (PDE5) and type 4 …

[HTML][HTML] Gene-environment interaction with smoking for increased non-muscle-invasive bladder cancer tumor size

N Lipunova, A Wesselius, KK Cheng… - Translational …, 2020 - ncbi.nlm.nih.gov
Background Urinary bladder cancer (UBC) is one of few cancers with an established gene-
environment interaction (GxE) with smoking. However, it is unknown whether the interaction …

The functions of hydrogen sulfide on the urogenital system of both males and females: from inception to the present

S Salehiyeh, AF Faiz, M Manzourolhojeh… - Naunyn-Schmiedeberg's …, 2024 - Springer
Hydrogen sulfide (H2S) is known as a chemical gas in nature with both enzymatic and non-
enzymatic biosynthesis in different human organs. A couple of studies have demonstrated …

A dual-emission fluorescence-enhanced probe for hydrogen sulfide and its application in biological imaging

M Li, Y Jiao, C Duan - New Journal of Chemistry, 2022 - pubs.rsc.org
Hydrogen sulfide (H2S) is an emerging gasotransmitter in the regulation of numerous
physiological and pathological processes. Herein, we reported a dual-emission …

THE INVESTIGATION OF THE ACTION MECHANISM OF AMMONIUM PYRROLIDINE DITHIOCARBAMATE ON RAT BLADDER SMOOTH MUSCLE CONTRACTION …

H Dayıoğlu, A Yılmaz, A Erdoğan, F Alan… - Journal of Scientific …, 2020 - dergipark.org.tr
Ammonium pyrrolidine dithiocarbamate (PDTC), the specific inhibitor of NF-κB, is a thiol
compound with anti-viral, anti-apoptotic, anti-inflammatory and antioxidant effects proven in …